General information
PDB ID 1AU7
Title PIT-1 MUTANT/DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 1997-09-12
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.3
Kind dna
Organism RATTUS NORVEGICUS
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1au7.pdb AB CD 0
Biounits:
1au7.pdb1.pdb AB CD 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
Pou Domain 3.3e-34 1 CL0123 A 6 75 CD
Homeobox Domain 3e-18 1 CL0123 A 76 158 CD
Pou Domain 1.5e-33 1 CL0123 B 6 103 CD
Homeobox Domain 2.1e-18 1 CL0123 B 74 158 CD
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Pit-1 POU homeodomain A 103 160 CD  H-Bb H-Mj L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Pit-1 POU homeodomain B 103 160 CD  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Pit-1 A 5 76 CD  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Pit-1 B 5 74 CD  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=132-273 C nucleus
A/B=132-273 F transcription corepressor activity
A/B=132-273 F sequence-specific DNA binding
A/B=132-273 F sequence-specific DNA binding transcription factor activity
A/B=132-273 P adenohypophysis development
A/B=132-273 P transcription, DNA-dependent
A/B=132-273 P negative regulation of transcription from RNA polymerase II promoter
A/B=132-273 P positive regulation of transcription from RNA polymerase II promoter
A/B=132-273 P nuclear transport
Sequences
Download file with secondary structure created by Stride  
1au7.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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