General information
PDB ID 1CQT
Title CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT
PDB header GENE REGULATION/DNA
Date 1999-08-11
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1cqt.pdb ABIJ MNOP 0
Biounits:
1cqt.pdb1.pdb AI MN 1
1cqt.pdb2.pdb BJ OP 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
Pou Domain 2.8e-39 1 CL0123 A 4 75 MN
Homeobox Domain 2.6e-18 1 CL0123 A 102 158 MN
Pou Domain 3.4e-36 1 CL0123 B 505 575 OP
Homeobox Domain 0.000000000000022 1 CL0123 B 602 658 OP
PD-C2-AF1 Domain 0.000000000042 1 No_clan I 300 321 MN
PD-C2-AF1 Domain 0.0000000000074 1 No_clan J 800 822 OP
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Oct-1 POU Homeodomain A 102 161 MN  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Oct-1 POU Homeodomain B 602 661 OP  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Oct-1 A 2 75 MN  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Oct-1 B 505 575 OP  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=280-438 C transcription factor complex
A/B=280-438 C nucleoplasm
A/B=280-438 F sequence-specific DNA binding
A/B=280-438 F sequence-specific DNA binding transcription factor activity
A/B=280-438 P negative regulation of transcription, DNA-dependent
A/B=280-438 P positive regulation of transcription from RNA polymerase II promoter
A/B=280-438 P transcription from RNA polymerase III promoter
A/B=280-438 P lens induction in camera-type eye
A/B=280-438 P olfactory placode formation
I/J=1-44 C nucleus
I/J=1-44 F DNA binding
I/J=1-44 F transcription coactivator activity
I/J=1-44 P transcription from RNA polymerase II promoter
I/J=1-44 P regulation of transcription, DNA-dependent
I/J=1-44 P humoral immune response
Sequences
Download file with secondary structure created by Stride  
1cqt.pdb1.pdb:   [ download sequences in FASTA format ]
M (dna): 
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N (dna): 
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A (protein): 
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I (protein): 
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1cqt.pdb2.pdb:   [ download sequences in FASTA format ]
O (dna): 
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P (dna): 
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B (protein): 
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J (protein): 
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