General information
PDB ID 1GT0
Title CRYSTAL STRUCTURE OF A POU/HMG/DNA TERNARY COMPLEX
PDB header TRANSCRIPTION
Date 2002-01-09
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism MUS MUSCULUS
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1gt0.pdb CD AB 0
Biounits:
1gt0.pdb1.pdb CD AB 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
Pou Domain 3.6e-38 1 CL0123 C 4 75 AB
Homeobox Domain 1.6e-17 1 CL0123 C 102 158 AB
HMG_box Domain 5.4e-29 1 CL0114 D 3 71 AB
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Oct-1 POU Homeodomain C 97 159 AB  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Oct-1 C 3 77 AB  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: HMG-box
    Superfamily: HMG-box
      Family: HMG-box
Sox-2 D N/A N/A AB  H-Bb H-Mn L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
C=280-438 C nucleoplasm
C=280-438 P negative regulation of transcription, DNA-dependent
C=280-438 P transcription from RNA polymerase III promoter
D=41-120 C cytoplasm
D=41-120 C transcription factor complex
D=41-120 F sequence-specific DNA binding
D=41-120 F sequence-specific DNA binding transcription factor activity
D=41-120 F chromatin binding
D=41-120 F transcription regulatory region DNA binding
D=41-120 P lung alveolus development
D=41-120 P diencephalon morphogenesis
D=41-120 P response to retinoic acid
D=41-120 P neuron fate commitment
D=41-120 P positive regulation of transcription from RNA polymerase II promoter
D=41-120 P negative regulation of osteoblast differentiation
D=41-120 P neuronal stem cell maintenance
D=41-120 P inner ear morphogenesis
D=41-120 P negative regulation of neuron differentiation
D=41-120 P negative regulation of canonical Wnt receptor signaling pathway
D=41-120 P tongue development
D=41-120 P epithelial tube branching involved in lung morphogenesis
D=41-120 P positive regulation of neuron differentiation
D=41-120 P detection of mechanical stimulus involved in equilibrioception
D=41-120 P adenohypophysis development
D=41-120 P endodermal cell fate specification
D=41-120 P retina morphogenesis in camera-type eye
D=41-120 P positive regulation of epithelial cell differentiation
D=41-120 P negative regulation of transcription from RNA polymerase II promoter
D=41-120 P positive regulation of neuroblast proliferation
D=41-120 P pigment biosynthetic process
D=41-120 P male genitalia development
D=41-120 P olfactory placode formation
D=41-120 P lens induction in camera-type eye
D=41-120 P forebrain neuron differentiation
D=41-120 P transcription, DNA-dependent
D=41-120 P detection of mechanical stimulus involved in sensory perception of sound
D=41-120 P positive regulation of Notch signaling pathway
D=41-120 P cerebral cortex development
Sequences
Download file with secondary structure created by Stride  
1gt0.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (protein): 
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D (protein): 
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