General information
PDB ID 1IG7
Title MSX-1 HOMEODOMAIN/DNA COMPLEX STRUCTURE
PDB header TRANSCRIPTION/DNA
Date 2001-04-17
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.2
Kind dna
Organism MUS MUSCULUS
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1ig7.pdb A BC 0
Biounits:
1ig7.pdb1.pdb A BC 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
Homeobox Domain 8.8e-23 1 CL0123 A 102 158 BC
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Msx-1 homeodomain A N/A N/A BC  H-Bb H-Mj L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
A=167-224 C transcription factor complex
A=167-224 F sequence-specific DNA binding
A=167-224 F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
A=167-224 P negative regulation of transcription regulatory region DNA binding
A=167-224 P odontogenesis of dentin-containing tooth
A=167-224 P face morphogenesis
A=167-224 P embryonic nail plate morphogenesis
A=167-224 P midbrain development
A=167-224 P protein stabilization
A=167-224 P epithelial to mesenchymal transition involved in endocardial cushion formation
A=167-224 P embryonic hindlimb morphogenesis
A=167-224 P negative regulation of cell growth
A=167-224 P positive regulation of transcription from RNA polymerase II promoter
A=167-224 P anterior/posterior pattern specification
A=167-224 P in utero embryonic development
A=167-224 P negative regulation of striated muscle cell differentiation
A=167-224 P muscle organ development
A=167-224 P cartilage morphogenesis
A=167-224 P protein localization to nucleus
A=167-224 P negative regulation of apoptotic process
A=167-224 P palate development
A=167-224 P mammary gland epithelium development
A=167-224 P BMP signaling pathway involved in heart development
A=167-224 P middle ear morphogenesis
A=167-224 P forebrain development
A=167-224 P embryonic forelimb morphogenesis
A=167-224 P mesenchymal cell proliferation
A=167-224 P positive regulation of BMP signaling pathway
A=167-224 P stem cell differentiation
A=167-224 P negative regulation of transcription from RNA polymerase II promoter
A=167-224 P negative regulation of cell proliferation
A=167-224 P apoptotic nuclear change
A=167-224 P bone morphogenesis
A=167-224 P positive regulation of apoptotic process
A=167-224 P regulation of odontogenesis
A=167-224 P signal transduction involved in regulation of gene expression
Sequences
Download file with secondary structure created by Stride  
1ig7.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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