NPIDB: 1XSL structure

General information

PDB ID

1XSL

Title

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH A ONE NUCLEOTIDE DNA GAP

PDB header

TRANSFERASE/DNA

Date

2004-10-19

Experimental method

X-RAY DIFFRACTION

Resolution (A)

2.3

Kind

dna

Organism

HOMO SAPIENS


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PDB	PDBe	MMDB	Jena	OCA
CATH	PDBsum	HSSP	PDBePISA	UniProt
ProteopediA	BIPA
		PDIdb

Composition of PDB entry and biounits
File:	Protein chains:	DNA chains:	RNA chains:	No. of models:	Action:

PDB entry:

pdb1xsl.pdb	AEIM	BCDFGHJKLNOP		0

Biounits:

1xsl.pdb1.pdb	A	BCD		1
1xsl.pdb2.pdb	E	FGH		1
1xsl.pdb3.pdb	I	JKL		1
1xsl.pdb4.pdb	M	NOP		1

Pfam domains
Name:	Type:	Domain:	E-value:	Significance:	Clan:	Prot. chain:	Start res.:	End res.:	Nuc. chains:	Int. mode:	Action:

DNA_pol_B_palm	Domain	Q9UGP5_386-496	6.9e-36	1	CL0260	A	386	496	BC
DNA_pol_lambd_f	Domain	Q9UGP5_336-384	5.6e-21	1	CL0198	A	336	384	BC
HHH_8	Domain	Q9UGP5_253-318	2.6e-18	1	CL0198	A	253	318	DB
DNA_pol_B_palm	Domain	Q9UGP5_386-496	6.8e-36	1	CL0260	E	386	496	FG
DNA_pol_lambd_f	Domain	Q9UGP5_336-384	5.5e-21	1	CL0198	E	336	384	FG
HHH_8	Domain	Q9UGP5_253-318	2.6e-18	1	CL0198	E	253	318	HF
DNA_pol_B_palm	Domain	Q9UGP5_386-496	6.9e-36	1	CL0260	I	386	496	JK
DNA_pol_lambd_f	Domain	Q9UGP5_336-384	5.6e-21	1	CL0198	I	336	384	JK
HHH_8	Domain	Q9UGP5_253-318	2.6e-18	1	CL0198	I	253	318	LJ
DNA_pol_B_palm	Domain	Q9UGP5_386-496	6.9e-36	1	CL0260	M	386	496	NO
DNA_pol_lambd_f	Domain	Q9UGP5_336-384	5.6e-21	1	CL0198	M	336	384	NO
HHH_8	Domain	Q9UGP5_253-318	2.6e-18	1	CL0198	M	253	318	PN
DNA_pol_B_thumb	Family	Q9UGP5_502-574	5.3e-22	1	No_clan	A	502	574	BC
DNA_pol_B_thumb	Family	Q9UGP5_502-574	5.2e-22	1	No_clan	E	502	574	FG
DNA_pol_B_thumb	Family	Q9UGP5_502-574	5.3e-22	1	No_clan	I	502	574	JK
DNA_pol_B_thumb	Family	Q9UGP5_502-574	5.3e-22	1	No_clan	M	502	574	NO

SCOP domains
Classification:	Protein:	Prot. chain:	Start res.:	End res.:	Nuc. chains:	Int. mode:	Action:

Class: All alpha proteins Fold: SAM domain-like Superfamily: DNA polymerase beta, N-terminal domain-like Family: DNA polymerase beta, N-terminal domain-like	DNA polymerase lambda	A	249	327	DB	H-Bb L-Bb
Class: All alpha proteins Fold: SAM domain-like Superfamily: DNA polymerase beta, N-terminal domain-like Family: DNA polymerase beta, N-terminal domain-like	DNA polymerase lambda	E	251	327	HF	H-Bb L-Bb
Class: All alpha proteins Fold: SAM domain-like Superfamily: DNA polymerase beta, N-terminal domain-like Family: DNA polymerase beta, N-terminal domain-like	DNA polymerase lambda	I	250	327	LJ	H-Bb L-Bb
Class: All alpha proteins Fold: SAM domain-like Superfamily: DNA polymerase beta, N-terminal domain-like Family: DNA polymerase beta, N-terminal domain-like	DNA polymerase lambda	M	249	327	PN	H-Bb L-Bb
Class: All alpha proteins Fold: SAM domain-like Superfamily: PsbU/PolX domain-like Family: DNA polymerase beta-like, second domain	DNA polymerase lambda	A	329	385	BC	-
Class: Alpha and beta proteins (a+b) Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like	DNA polymerase lambda	A	386	575	BC	-
Class: All alpha proteins Fold: SAM domain-like Superfamily: PsbU/PolX domain-like Family: DNA polymerase beta-like, second domain	DNA polymerase lambda	E	329	385	FG	-
Class: Alpha and beta proteins (a+b) Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like	DNA polymerase lambda	E	386	575	FG	-
Class: All alpha proteins Fold: SAM domain-like Superfamily: PsbU/PolX domain-like Family: DNA polymerase beta-like, second domain	DNA polymerase lambda	I	329	385	JK	-
Class: Alpha and beta proteins (a+b) Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like	DNA polymerase lambda	I	386	575	JK	-
Class: All alpha proteins Fold: SAM domain-like Superfamily: PsbU/PolX domain-like Family: DNA polymerase beta-like, second domain	DNA polymerase lambda	M	329	385	NO	-
Class: Alpha and beta proteins (a+b) Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like	DNA polymerase lambda	M	386	575	NO	-

GO terms
Protein chains:	GO type:	GO description:
A/E/I/M=242-575	C	nucleus
A/E/I/M=242-575	F	lyase activity
A/E/I/M=242-575	F	DNA-directed DNA polymerase activity
A/E/I/M=242-575	F	DNA binding
A/E/I/M=242-575	F	metal ion binding
A/E/I/M=242-575	P	nucleotide-excision repair
A/E/I/M=242-575	P	DNA replication
A/E/I/M=242-575	P	somatic hypermutation of immunoglobulin genes

Sequences

Download file with secondary structure created by Stride

1xsl.pdb1.pdb: [ download sequences in FASTA format ]

B (dna):