General information
PDB ID 1B72
Title PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
PDB header PROTEIN/DNA
Date 1999-01-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.35
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1b72.pdb AB DE 0
Biounits:
1b72.pdb1.pdb AB DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeodomain Domain P14653_206-260 6.2e-23 1 CL0123 A 184 260 DE  H-Bb H-Mj L-Bb L-Mn 
Homeodomain Domain P40424_235-293 2.8e-20 1 CL0123 B 235 293 DE  H-Bb H-Mj L-Bb L-Mn 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
pbx1 B N/A N/A DE  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Homeobox protein hox-b1 A N/A N/A DE  H-Bb H-Mj L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
A=170-264 C nuclear chromatin
A=170-264 F DNA binding
A=170-264 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=170-264 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=170-264 F protein domain specific binding
A=170-264 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=170-264 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A=170-264 F sequence-specific double-stranded DNA binding
A=170-264 P anatomical structure formation involved in morphogenesis
A=170-264 P anterior/posterior pattern specification
A=170-264 P embryonic skeletal system morphogenesis
A=170-264 P facial nerve structural organization
A=170-264 P facial nucleus development
A=170-264 P multicellular organism development
A=170-264 P pattern specification process
A=170-264 P positive regulation of transcription by RNA polymerase II
A=170-264 P regulation of transcription, DNA-templated
A=170-264 P rhombomere 4 development
A=170-264 P rhombomere 5 development
B=233-319 C cytoplasm
B=233-319 C nuclear chromatin
B=233-319 C nucleoplasm
B=233-319 C nucleus
B=233-319 C RNA polymerase II transcription regulator complex
B=233-319 F DNA binding
B=233-319 F DNA-binding transcription activator activity, RNA polymerase II-specific
B=233-319 F DNA-binding transcription factor activity
B=233-319 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=233-319 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
B=233-319 F sequence-specific double-stranded DNA binding
B=233-319 F transcription factor binding
B=233-319 P adrenal gland development
B=233-319 P animal organ morphogenesis
B=233-319 P anterior/posterior pattern specification
B=233-319 P brain development
B=233-319 P branching involved in ureteric bud morphogenesis
B=233-319 P embryonic hemopoiesis
B=233-319 P embryonic limb morphogenesis
B=233-319 P embryonic organ development
B=233-319 P embryonic skeletal system development
B=233-319 P eye development
B=233-319 P negative regulation of DNA-binding transcription factor activity
B=233-319 P negative regulation of neuron differentiation
B=233-319 P neuron development
B=233-319 P positive regulation of cell population proliferation
B=233-319 P positive regulation of G2/M transition of mitotic cell cycle
B=233-319 P positive regulation of transcription of Notch receptor target
B=233-319 P proximal/distal pattern formation
B=233-319 P regulation of ossification
B=233-319 P sex differentiation
B=233-319 P somatic stem cell population maintenance
B=233-319 P spleen development
B=233-319 P steroid biosynthetic process
B=233-319 P thymus development
Sequences
Download file with secondary structure created by Stride  
1b72.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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E (dna): 
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A (protein): 
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B (protein): 
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