General information
PDB ID 1BF5
Title TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
PDB header GENE REGULATION/DNA
Date 1998-05-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.9
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1bf5.pdb A BC 0
Biounits:
1bf5.pdb1.pdb A BC 0
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
STAT_bind Domain P42224_321-458 1.2e-79 1 CL0073 A 317 566 BC  H-Bb H-Mj L-Bb L-Mj 
SH2 Domain P42224_573-657 1.5e-09 1 CL0541 A 573 658   
STAT_alpha Family P42224_139-309 1e-48 1 No_clan A 139 315   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: STAT DNA-binding domain
STAT-1, DNA-binding domain A 317 568 BC  L-Bb L-Mj L-Mn 
Class: All alpha proteins
  Fold: STAT-like
    Superfamily: STAT
      Family: STAT
STAT-1, coiled coil domain A 136 316 -
Class: Alpha and beta proteins (a+b)
  Fold: SH2-like
    Superfamily: SH2 domain
      Family: SH2 domain
STAT-1 A 569 710 -
GO terms
Protein chains: GO type: GO description:
A=136-710 C axon
A=136-710 C nucleoplasm
A=136-710 C nucleolus
A=136-710 C dendrite
A=136-710 C cytosol
A=136-710 F sequence-specific DNA binding transcription factor activity
A=136-710 F RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
A=136-710 F double-stranded DNA binding
A=136-710 F signal transducer activity
A=136-710 F RNA polymerase II core promoter sequence-specific DNA binding
A=136-710 F calcium ion binding
A=136-710 P renal tubule development
A=136-710 P negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
A=136-710 P negative regulation of transcription from RNA polymerase II promoter
A=136-710 P virus-host interaction
A=136-710 P response to exogenous dsRNA
A=136-710 P metanephric mesenchymal cell differentiation
A=136-710 P interferon-gamma-mediated signaling pathway
A=136-710 P type I interferon-mediated signaling pathway
A=136-710 P blood circulation
A=136-710 P positive regulation of transcription, DNA-dependent
A=136-710 P positive regulation of mesenchymal cell proliferation
A=136-710 P negative regulation of angiogenesis
A=136-710 P JAK-STAT cascade involved in growth hormone signaling pathway
A=136-710 P negative regulation of metanephric nephron tubule epithelial cell differentiation
A=136-710 P lipopolysaccharide-mediated signaling pathway
A=136-710 P positive regulation of smooth muscle cell proliferation
A=136-710 P positive regulation of transcription from RNA polymerase II promoter
A=136-710 P metanephric mesenchymal cell proliferation involved in metanephros development
A=136-710 P regulation of interferon-gamma-mediated signaling pathway
A=136-710 P negative regulation of I-kappaB kinase/NF-kappaB cascade
A=136-710 P regulation of type I interferon-mediated signaling pathway
A=136-710 P induction of apoptosis
A=136-710 P negative regulation of endothelial cell proliferation
A=136-710 P response to virus
A=136-710 P tumor necrosis factor-mediated signaling pathway
A=136-710 P response to cAMP
Sequences
Download file with secondary structure created by Stride  
1bf5.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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