General information
PDB ID 1C0W
Title CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
PDB header GENE REGULATION/DNA
Date 1999-07-22
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.2
Kind dna
Organism CORYNEBACTERIUM DIPHTHERIAE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1c0w.pdb ABCD EF 0
Biounits:
1c0w.pdb1.pdb ABCD EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Fe_dep_repr_C Domain P0DJL7_65-134 6.4e-26 1 CL0123 A 65 134   
Fe_dep_repress Domain P0DJL7_3-62 4.1e-20 1 CL0123 A 3 62 EF  H-Bb H-Mj L-Bb L-Mj 
DtxR Domain P0DJL7_165-223 2.4e-05 0 CL0206 A 135 211   
DtxR Domain P0DJL7_147-225 2e-34 1 CL0206 B 147 225   
Fe_dep_repr_C Domain P0DJL7_65-134 1.1e-25 1 CL0123 B 65 134   
Fe_dep_repress Domain P0DJL7_3-62 6.5e-20 1 CL0123 B 3 62 EF  H-Bb H-Mj L-Bb L-Mj 
Fe_dep_repr_C Domain P0DJL7_65-134 6.6e-26 1 CL0123 C 65 134   
Fe_dep_repress Domain P0DJL7_3-62 4.2e-20 1 CL0123 C 3 62 EF  H-Bb H-Mj L-Bb L-Mj 
DtxR Domain P0DJL7_165-223 1.8e-07 1 CL0206 C 136 212   
Fe_dep_repr_C Domain P0DJL7_65-134 6.6e-26 1 CL0123 D 65 134   
Fe_dep_repress Domain P0DJL7_3-62 4.2e-20 1 CL0123 D 3 62 EF  H-Bb H-Mj L-Bb L-Mj 
DtxR Domain P0DJL7_165-223 2.6e-07 1 CL0206 D 134 211   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Iron-dependent repressor protein
Diphtheria toxin repressor (DtxR) A 2 64 EF  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Iron-dependent repressor protein
Diphtheria toxin repressor (DtxR) B 2 64 EF  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Iron-dependent repressor protein
Diphtheria toxin repressor (DtxR) C 2 64 EF  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Iron-dependent repressor protein
Diphtheria toxin repressor (DtxR) D 2 64 EF  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: Iron-dependent repressor protein, dimerization domain
    Superfamily: Iron-dependent repressor protein, dimerization domain
      Family: Iron-dependent repressor protein, dimerization domain
Diphtheria toxin repressor (DtxR) A 65 140 -
Class: All alpha proteins
  Fold: Iron-dependent repressor protein, dimerization domain
    Superfamily: Iron-dependent repressor protein, dimerization domain
      Family: Iron-dependent repressor protein, dimerization domain
Diphtheria toxin repressor (DtxR) B 65 140 -
Class: All alpha proteins
  Fold: Iron-dependent repressor protein, dimerization domain
    Superfamily: Iron-dependent repressor protein, dimerization domain
      Family: Iron-dependent repressor protein, dimerization domain
Diphtheria toxin repressor (DtxR) C 65 140 -
Class: All alpha proteins
  Fold: Iron-dependent repressor protein, dimerization domain
    Superfamily: Iron-dependent repressor protein, dimerization domain
      Family: Iron-dependent repressor protein, dimerization domain
Diphtheria toxin repressor (DtxR) D 65 140 -
Class: All beta proteins
  Fold: SH3-like barrel
    Superfamily: C-terminal domain of transcriptional repressors
      Family: FeoA-like
Diphtheria toxin repressor (DtxR) B 147 226 -
Class: All beta proteins
  Fold: SH3-like barrel
    Superfamily: C-terminal domain of transcriptional repressors
      Family: FeoA-like
Diphtheria toxin repressor (DtxR) A 165 223 -
Class: All beta proteins
  Fold: SH3-like barrel
    Superfamily: C-terminal domain of transcriptional repressors
      Family: FeoA-like
Diphtheria toxin repressor (DtxR) C 165 222 -
Class: All beta proteins
  Fold: SH3-like barrel
    Superfamily: C-terminal domain of transcriptional repressors
      Family: FeoA-like
Diphtheria toxin repressor (DtxR) D 166 222 -
GO terms
Protein chains: GO type: GO description:
A/B/C/D=2-226 C cytoplasm
A/B/C/D=2-226 F DNA binding
A/B/C/D=2-226 F DNA-binding transcription factor activity
A/B/C/D=2-226 F identical protein binding
A/B/C/D=2-226 F protein dimerization activity
A/B/C/D=2-226 F SH3 domain binding
A/B/C/D=2-226 F transition metal ion binding
Sequences
Download file with secondary structure created by Stride  
1c0w.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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