General information
PDB ID 1CQT
Title CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT
PDB header GENE REGULATION/DNA
Date 1999-08-11
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1cqt.pdb ABIJ MNOP 0
Biounits:
1cqt.pdb1.pdb AI MN 1
1cqt.pdb2.pdb BJ OP 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Pou Domain P14859_283-354 2.9e-37 1 CL0123 A 4 75 MN  H-Bb H-Mj L-Bb L-Mj 
Homeodomain Domain P14859_380-436 1.4e-18 1 CL0123 A 102 158 MN  H-Bb H-Mj L-Bb L-Mn 
Pou Domain P14859_283-354 4.1e-34 1 CL0123 B 505 575 OP  H-Bb H-Mj L-Bb L-Mj 
Homeodomain Domain P14859_380-436 1.2e-14 1 CL0123 B 602 658 OP  H-Bb H-Mj L-Bb 
PD-C2-AF1 Domain Q16633_16-37 8.6e-10 1 No_clan I 300 321 MN  L-Bb L-Mj 
PD-C2-AF1 Domain Q16633_16-37 2.4e-10 1 No_clan J 800 822 OP  L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Oct-1 A 2 75 MN  H-Bb H-Mj L-Bb L-Mj 
Class: All alpha proteins
  Fold: lambda repressor-like DNA-binding domains
    Superfamily: lambda repressor-like DNA-binding domains
      Family: POU-specific domain
Oct-1 B 505 575 OP  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Oct-1 POU Homeodomain A 102 161 MN  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Oct-1 POU Homeodomain B 602 661 OP  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=278-439 C endoplasmic reticulum
A/B=278-439 C intracellular membrane-bounded organelle
A/B=278-439 C nuclear chromatin
A/B=278-439 C nucleoplasm
A/B=278-439 C nucleus
A/B=278-439 C RNA polymerase II transcription regulator complex
A/B=278-439 F DNA binding
A/B=278-439 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=278-439 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=278-439 F identical protein binding
A/B=278-439 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=278-439 F RNA polymerase II core promoter sequence-specific DNA binding
A/B=278-439 F sequence-specific DNA binding
A/B=278-439 P cell differentiation
A/B=278-439 P cytokine-mediated signaling pathway
A/B=278-439 P negative regulation of transcription, DNA-templated
A/B=278-439 P positive regulation of transcription by RNA polymerase II
A/B=278-439 P snRNA transcription by RNA polymerase II
I/J=1-44 C nucleus
I/J=1-44 C RNA polymerase II transcription regulator complex
I/J=1-44 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
I/J=1-44 F RNA polymerase II core promoter sequence-specific DNA binding
I/J=1-44 F transcription coactivator activity
I/J=1-44 F transcription coregulator activity
I/J=1-44 P cellular response to virus
I/J=1-44 P germinal center B cell differentiation
I/J=1-44 P humoral immune response
I/J=1-44 P positive regulation of interleukin-6 production
I/J=1-44 P positive regulation of transcription by RNA polymerase II
Sequences
Download file with secondary structure created by Stride  
1cqt.pdb1.pdb:   [ download sequences in FASTA format ]
M (dna): 
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N (dna): 
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A (protein): 
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I (protein): 
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1cqt.pdb2.pdb:   [ download sequences in FASTA format ]
O (dna): 
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P (dna): 
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B (protein): 
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J (protein): 
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