General information
PDB ID 1H6F
Title HUMAN TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FOR ULNAR-MAMMARY SYNDROME, BOUND TO A PALINDROMIC DNA SITE
PDB header TRANSCRIPTION FACTOR
Date 2001-06-13
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.7
Kind dna
Organism HOMO SAPIENS, SYNTHETIC
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1h6f.pdb AB CD 0
Biounits:
1h6f.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
T-box Domain O15119_105-305 3.5e-83 1 CL0073 A 105 285 CD  H-Bb H-Mn S-Bb L-Bb L-Mj 
T-box Domain O15119_105-305 3.6e-83 1 CL0073 B 105 285 CD  H-Bb H-Mn S-Bb S-Mj L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: T-box
T-box protein 3, tbx3 A N/A N/A CD  H-Bb H-Mn L-Bb L-Mj 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: T-box
T-box protein 3, tbx3 B N/A N/A CD  H-Bb H-Mn S-Bb S-Mj L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=101-311 C nuclear chromatin
A/B=101-311 C nucleus
A/B=101-311 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=101-311 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=101-311 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/B=101-311 F RNA polymerase II activating transcription factor binding
A/B=101-311 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=101-311 F RNA polymerase II transcription factor binding
A/B=101-311 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=101-311 F sequence-specific DNA binding
A/B=101-311 F sequence-specific double-stranded DNA binding
A/B=101-311 P animal organ morphogenesis
A/B=101-311 P anterior/posterior axis specification, embryo
A/B=101-311 P atrioventricular bundle cell differentiation
A/B=101-311 P blood vessel development
A/B=101-311 P branching involved in mammary gland duct morphogenesis
A/B=101-311 P cardiac chamber development
A/B=101-311 P cardiac muscle cell fate commitment
A/B=101-311 P cell aging
A/B=101-311 P cell fate specification
A/B=101-311 P cellular senescence
A/B=101-311 P central nervous system development
A/B=101-311 P embryonic digit morphogenesis
A/B=101-311 P embryonic forelimb morphogenesis
A/B=101-311 P embryonic hindlimb morphogenesis
A/B=101-311 P female genitalia development
A/B=101-311 P follicle-stimulating hormone secretion
A/B=101-311 P forelimb morphogenesis
A/B=101-311 P heart looping
A/B=101-311 P in utero embryonic development
A/B=101-311 P limbic system development
A/B=101-311 P luteinizing hormone secretion
A/B=101-311 P male genitalia development
A/B=101-311 P mammary gland development
A/B=101-311 P mammary placode formation
A/B=101-311 P mesoderm morphogenesis
A/B=101-311 P negative regulation of apoptotic process
A/B=101-311 P negative regulation of epithelial cell differentiation
A/B=101-311 P negative regulation of myoblast differentiation
A/B=101-311 P negative regulation of transcription by RNA polymerase II
A/B=101-311 P negative regulation of transcription, DNA-templated
A/B=101-311 P outflow tract morphogenesis
A/B=101-311 P positive regulation of cell cycle
A/B=101-311 P positive regulation of cell population proliferation
A/B=101-311 P positive regulation of stem cell proliferation
A/B=101-311 P positive regulation of transcription by RNA polymerase II
A/B=101-311 P regulation of transcription by RNA polymerase II
A/B=101-311 P roof of mouth development
A/B=101-311 P sinoatrial node cell development
A/B=101-311 P skeletal system development
A/B=101-311 P smooth muscle cell differentiation
A/B=101-311 P specification of animal organ position
A/B=101-311 P stem cell population maintenance
A/B=101-311 P ureteric peristalsis
A/B=101-311 P ventricular septum morphogenesis
Sequences
Download file with secondary structure created by Stride  
1h6f.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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