General information
PDB ID 1K6O
Title CRYSTAL STRUCTURE OF A TERNARY SAP-1/SRF/C-FOS SRE DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 2001-10-16
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.19
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1k6o.pdb ABC DE 0
Biounits:
1k6o.pdb1.pdb ABC DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Ets Domain P28324_6-85 3.9e-37 1 CL0123 A 306 385 DE  H-Bb H-Mj L-Bb 
SRF-TF Domain P11831_150-197 4.6e-21 1 No_clan B 150 197 DE  H-Bb H-Mj 
SRF-TF Domain P11831_150-197 4.4e-21 1 No_clan C 150 197 DE  H-Bb H-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: ets domain
Serum response factor accessory protein 1a, SAP-1 A N/A N/A DE  H-Bb H-Mj L-Bb 
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Serum response factor (SRF) core B N/A N/A DE  H-Bb H-Mj L-Bb L-Mn 
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Serum response factor (SRF) core C N/A N/A DE  H-Bb H-Mj L-Mn 
GO terms
Protein chains: GO type: GO description:
A=1-93 C cytoplasm
A=1-93 F sequence-specific DNA binding transcription factor activity
A=1-93 F DNA binding
A=1-93 F transcription cofactor activity
B/C=133-235 C nuclear chromatin
B/C=133-235 C nucleus
B/C=133-235 C endoplasmic reticulum
B/C=133-235 F sequence-specific DNA binding
B/C=133-235 F RNA polymerase II transcription factor binding transcription factor activity
B/C=133-235 F serum response element binding
B/C=133-235 F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
B/C=133-235 F chromatin DNA binding
B/C=133-235 F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
B/C=133-235 P contractile actin filament bundle assembly
B/C=133-235 P patterning of blood vessels
B/C=133-235 P regulation of cell adhesion
B/C=133-235 P cell-matrix adhesion
B/C=133-235 P epithelial cell-cell adhesion
B/C=133-235 P stress fiber assembly
B/C=133-235 P positive regulation of filopodium assembly
B/C=133-235 P long-term memory
B/C=133-235 P response to toxin
B/C=133-235 P cellular senescence
B/C=133-235 P morphogenesis of an epithelial sheet
B/C=133-235 P developmental growth
B/C=133-235 P dorsal aorta morphogenesis
B/C=133-235 P sarcomere organization
B/C=133-235 P heart trabecula formation
B/C=133-235 P erythrocyte development
B/C=133-235 P positive regulation of cell differentiation
B/C=133-235 P eyelid development in camera-type eye
B/C=133-235 P muscle cell homeostasis
B/C=133-235 P heart looping
B/C=133-235 P long term synaptic depression
B/C=133-235 P skin morphogenesis
B/C=133-235 P negative regulation of cell migration
B/C=133-235 P cardiac myofibril assembly
B/C=133-235 P positive regulation of transcription via serum response element binding
B/C=133-235 P regulation of smooth muscle cell differentiation
B/C=133-235 P neuron development
B/C=133-235 P primitive streak formation
B/C=133-235 P megakaryocyte development
B/C=133-235 P positive thymic T cell selection
B/C=133-235 P mesoderm formation
B/C=133-235 P hippocampus development
B/C=133-235 P platelet activation
B/C=133-235 P neuron migration
B/C=133-235 P epithelial structure maintenance
B/C=133-235 P positive regulation of transcription initiation from RNA polymerase II promoter
B/C=133-235 P hemopoietic stem cell differentiation
B/C=133-235 P response to hormone stimulus
B/C=133-235 P platelet formation
B/C=133-235 P tight junction assembly
B/C=133-235 P response to cytokine stimulus
B/C=133-235 P trophectodermal cell differentiation
B/C=133-235 P regulation of water loss via skin
B/C=133-235 P cardiac vascular smooth muscle cell differentiation
B/C=133-235 P neuron projection development
B/C=133-235 P angiogenesis involved in wound healing
B/C=133-235 P positive regulation of smooth muscle contraction
B/C=133-235 P cell migration involved in sprouting angiogenesis
B/C=133-235 P negative regulation of cell proliferation
B/C=133-235 P tangential migration from the subventricular zone to the olfactory bulb
B/C=133-235 P associative learning
Sequences
Download file with secondary structure created by Stride  
1k6o.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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E (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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