General information
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| PDB ID | 1LWS |
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| Title | CRYSTAL STRUCTURE OF THE INTEIN HOMING ENDONUCLEASE PI-SCEI BOUND TO ITS RECOGNITION SEQUENCE | ||||
| PDB header | HYDROLASE/DNA | ||||
| Date | 2002-06-03 | ||||
| Experimental method | X-RAY DIFFRACTION | ||||
| Resolution (A) | 3.5 | ||||
| Kind | dna | ||||
| Organism | SACCHAROMYCES CEREVISIAE | ||||
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Quick Links
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Composition of PDB entry and biounits
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| File: | Protein chains: | DNA chains: | RNA chains: | No. of models: | Action: |
| PDB entry: | |||||
| pdb1lws.pdb | A | BC | 0 |
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| Biounits: | |||||
| 1lws.pdb1.pdb | A | BC | 1 |
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Pfam domains
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| Name: | Type: | Domain: | E-value: | Significance: | Clan: | Prot. chain: | Start res.: | End res.: | Nuc. chains: | Int. mode: | Action: |
Hom_end_hint
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Domain | P17255_284-736 | 1e-72 | 1 |
CL0363
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A | 1 | 453 | BC | H-Bb H-Mj H-Mn S-Bb S-Mj L-Bb L-Mj L-Mn |
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Hom_end
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Domain | P17255_585-696 | 5.6e-35 | 1 |
CL0324
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A | 302 | 413 | BC | S-Bb S-Mj L-Bb L-Mj |
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Hom_end
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Domain | P17255_478-579 | 1.3e-08 | 1 |
CL0324
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A | 195 | 287 | BC | S-Bb L-Bb L-Mj |
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SCOP domains
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| Classification: | Protein: | Prot. chain: | Start res.: | End res.: | Nuc. chains: | Int. mode: | Action: |
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Class: Alpha and beta proteins (a+b)
Fold: Homing endonuclease-like
Superfamily: Homing endonucleases
Family: Intein endonuclease
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VMA1-derived endonuclease (VDE) PI-SceI | A | 181 | 298 | BC | S-Bb L-Bb L-Mj |
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Class: Alpha and beta proteins (a+b)
Fold: Homing endonuclease-like
Superfamily: Homing endonucleases
Family: Intein endonuclease
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VMA1-derived endonuclease (VDE) PI-SceI | A | 299 | 415 | BC | S-Bb S-Mj L-Bb L-Mj |
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Class: All beta proteins
Fold: Hedgehog/intein (Hint) domain
Superfamily: Hedgehog/intein (Hint) domain
Family: Intein (protein splicing domain)
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VMA1-derived endonuclease (VDE) PI-Scei intein | A | 1 | 180 | - |
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Class: All beta proteins
Fold: Hedgehog/intein (Hint) domain
Superfamily: Hedgehog/intein (Hint) domain
Family: Intein (protein splicing domain)
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VMA1-derived endonuclease (VDE) PI-Scei intein | A | 416 | 454 | - |
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Class: All beta proteins
Fold: Hedgehog/intein (Hint) domain
Superfamily: Hedgehog/intein (Hint) domain
Family: Intein (protein splicing domain)
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VMA1-derived endonuclease (VDE) PI-Scei intein | A | 1 | 180 | BC | - |
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Class: All beta proteins
Fold: Hedgehog/intein (Hint) domain
Superfamily: Hedgehog/intein (Hint) domain
Family: Intein (protein splicing domain)
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VMA1-derived endonuclease (VDE) PI-Scei intein | A | 416 | 454 | BC | - |
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| GO terms | ||
| Protein chains: | GO type: | GO description: |
| A=284-737 | C | endomembrane system |
| A=284-737 | C | fungal-type vacuole membrane |
| A=284-737 | C | plasma membrane |
| A=284-737 | C | vacuolar membrane |
| A=284-737 | C | vacuolar proton-transporting V-type ATPase, V1 domain |
| A=284-737 | F | ATP binding |
| A=284-737 | F | DNA binding |
| A=284-737 | F | endonuclease activity |
| A=284-737 | F | mRNA binding |
| A=284-737 | F | proton-transporting ATP synthase activity, rotational mechanism |
| A=284-737 | F | proton-transporting ATPase activity, rotational mechanism |
| A=284-737 | P | cellular protein metabolic process |
| A=284-737 | P | intein-mediated protein splicing |
| A=284-737 | P | intron homing |
| A=284-737 | P | vacuolar acidification |
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Sequences
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Download file with secondary structure created by Stride
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1lws.pdb1.pdb:
[
download sequences in FASTA format
]
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B (dna):
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C (dna):
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A (protein):
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