General information
PDB ID 1MJE
Title STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX
PDB header GENE REGULATION/ANTITUMOR PROTEIN/DNA
Date 2002-08-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.5
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1mje.pdb BA C 0
Biounits:
1mje.pdb1.pdb BA C 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
BRCA-2_helical Domain 4.2e-92 1 No_clan A 2402 2588
BRCA-2_OB3 Domain 1.4e-46 1 CL0021 A 2971 3105 C
BRCA-2_OB1 Domain 2.9e-35 1 CL0021 A 2591 2717
Tower Domain 2.9e-18 1 No_clan A 2752 2792 C
DSS1_SEM1 Family 0.0000000022 1 No_clan B 7 62
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: BRCA2 helical domain
    Superfamily: BRCA2 helical domain
      Family: BRCA2 helical domain
BRCA2 helical domain A 2399 2589 -
Class: All alpha proteins
  Fold: BRCA2 tower domain
    Superfamily: BRCA2 tower domain
      Family: BRCA2 tower domain
BRCA2 tower domain A 2752 2887 C -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2590 2722 -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2723 2751 C -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2888 2970 C -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2723 2751 -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2888 2970 -
Class: All beta proteins
  Fold: OB-fold
    Superfamily: Nucleic acid-binding proteins
      Family: Single strand DNA-binding domain, SSB
OB-fold domains of BRCA2 A 2971 3110 C -
GO terms
Protein chains: GO type: GO description:
A=2378-2793 C centrosome
A=2378-2793 C nucleoplasm
A=2378-2793 F single-stranded DNA binding
A=2378-2793 P centrosome duplication
A=2378-2793 P regulation of cytokinesis
A=2378-2793 P hemopoiesis
A=2378-2793 P response to UV-C
A=2378-2793 P DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
A=2378-2793 P regulation of S phase of mitotic cell cycle
A=2378-2793 P response to X-ray
A=2378-2793 P inner cell mass cell proliferation
A=2378-2793 P response to gamma radiation
A=2378-2793 P brain development
A=2378-2793 P male meiosis I
A=2378-2793 P positive regulation of mitotic cell cycle
A=2378-2793 P cell aging
A=2378-2793 P replication fork protection
A=2378-2793 P female gonad development
A=2378-2793 P DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
A=2378-2793 P oocyte maturation
A=2378-2793 P spermatogenesis
A=2378-2793 P chromosome organization
A=2378-2793 P regulation of cell proliferation
B=1-70 C proteasome complex
B=1-70 F peptidase activity
B=1-70 P proteolysis
B=1-70 P double-strand break repair via homologous recombination
Sequences
Download file with secondary structure created by Stride  
1mje.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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A (protein): 
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B (protein): 
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