General information
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| PDB ID | 1N6J |
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| Title | STRUCTURAL BASIS OF SEQUENCE-SPECIFIC RECRUITMENT OF HISTONE DEACETYLASES BY MYOCYTE ENHANCER FACTOR-2 | ||||
| PDB header | TRANSCRIPTION/DNA | ||||
| Date | 2002-11-11 | ||||
| Experimental method | X-RAY DIFFRACTION | ||||
| Resolution (A) | 2.2 | ||||
| Kind | dna | ||||
| Organism | HOMO SAPIENS | ||||
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Quick Links
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Composition of PDB entry and biounits
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| File: | Protein chains: | DNA chains: | RNA chains: | No. of models: | Action: |
| PDB entry: | |||||
| pdb1n6j.pdb | ABG | CD | 2 |
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| Biounits: | |||||
| 1n6j.pdb1.pdb | ABG | CD | 1 |
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Pfam domains
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| Name: | Type: | Domain: | E-value: | Significance: | Clan: | Prot. chain: | Start res.: | End res.: | Nuc. chains: | Int. mode: | Action: |
SRF-TF
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Domain | Q02080_10-57 | 2.7e-24 | 1 | No_clan | A | 10 | 57 | CD | H-Bb H-Mj |
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SRF-TF
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Domain | Q02080_10-57 | 2.5e-24 | 1 | No_clan | B | 10 | 57 | CD | H-Bb H-Mj |
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MEF2_binding
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Domain | Q9Y6J0_2159-2184 | 4.6e-18 | 1 | No_clan | G | 101 | 126 |
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SCOP domains
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| Classification: | Protein: | Prot. chain: | Start res.: | End res.: | Nuc. chains: | Int. mode: | Action: |
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Class: Alpha and beta proteins (a+b)
Fold: SRF-like
Superfamily: SRF-like
Family: SRF-like
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Myocyte enhancer factor Mef2b core | A | N/A | N/A | CD | H-Bb L-Mn |
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Class: Alpha and beta proteins (a+b)
Fold: SRF-like
Superfamily: SRF-like
Family: SRF-like
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Myocyte enhancer factor Mef2b core | B | N/A | N/A | CD | H-Bb H-Mj L-Bb L-Mn |
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| GO terms | ||
| Protein chains: | GO type: | GO description: |
| A/B=2-94 | C | cell junction |
| A/B=2-94 | C | cytosol |
| A/B=2-94 | C | nuclear chromatin |
| A/B=2-94 | C | nucleoplasm |
| A/B=2-94 | C | nucleus |
| A/B=2-94 | C | transcription regulator complex |
| A/B=2-94 | F | DNA-binding transcription activator activity, RNA polymerase II-specific |
| A/B=2-94 | F | DNA-binding transcription factor activity |
| A/B=2-94 | F | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A/B=2-94 | F | histone deacetylase binding |
| A/B=2-94 | F | protein dimerization activity |
| A/B=2-94 | F | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| A/B=2-94 | F | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| A/B=2-94 | F | sequence-specific DNA binding |
| A/B=2-94 | F | sequence-specific double-stranded DNA binding |
| A/B=2-94 | F | transcription factor binding |
| A/B=2-94 | F | transcription regulatory region sequence-specific DNA binding |
| A/B=2-94 | P | cell differentiation |
| A/B=2-94 | P | muscle organ development |
| A/B=2-94 | P | positive regulation of transcription by RNA polymerase II |
| G=2156-2190 | C | aggresome |
| G=2156-2190 | C | cytosol |
| G=2156-2190 | C | nucleoplasm |
| G=2156-2190 | C | nucleus |
| G=2156-2190 | F | protein phosphatase inhibitor activity |
| G=2156-2190 | P | cell surface receptor signaling pathway |
| G=2156-2190 | P | DNA replication-independent nucleosome assembly |
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Sequences
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Download file with secondary structure created by Stride
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1n6j.pdb1.pdb:
[
download sequences in FASTA format
]
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C (dna):
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D (dna):
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A (protein):
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B (protein):
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G (protein):
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