General information
PDB ID 1NFK
Title STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER
PDB header TRANSCRIPTION/DNA
Date 1995-02-28
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.3
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1nfk.pdb AB CD 0
Biounits:
1nfk.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RHD_DNA_bind Domain P25799_42-240 7.2e-74 1 CL0073 A 42 240 CD  S-Mj L-Bb L-Mj 
RHD_dimer Domain P25799_249-350 5.5e-42 1 CL0159 A 249 350 C  L-Bb 
RHD_DNA_bind Domain P25799_42-240 7.2e-74 1 CL0073 B 42 240 CD  S-Bb S-Mj L-Bb L-Mj 
RHD_dimer Domain P25799_249-350 5.5e-42 1 CL0159 B 249 350 D  L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
p50 subunit of NF-kappa B transcription factor A 251 350 C  L-Bb 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
p50 subunit of NF-kappa B transcription factor B 251 350 D  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
p50 subunit of NF-kappa B (NFKB), N-terminal domain A 39 250 CD  L-Bb L-Mj 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
p50 subunit of NF-kappa B (NFKB), N-terminal domain B 39 250 CD  S-Bb S-Mj L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=39-363 C protein complex
A/B=39-363 C mitochondrion
A/B=39-363 C cytosol
A/B=39-363 C nucleus
A/B=39-363 F transcription regulatory region sequence-specific DNA binding
A/B=39-363 F sequence-specific DNA binding transcription factor activity
A/B=39-363 F double-stranded DNA binding
A/B=39-363 F sequence-specific DNA binding
A/B=39-363 F regulatory region DNA binding
A/B=39-363 F nucleic acid binding transcription factor activity
A/B=39-363 P lymph node development
A/B=39-363 P positive regulation of hyaluronan biosynthetic process
A/B=39-363 P positive regulation of transcription from RNA polymerase II promoter
A/B=39-363 P negative regulation of calcidiol 1-monooxygenase activity
A/B=39-363 P cellular response to mechanical stimulus
A/B=39-363 P signal transduction
A/B=39-363 P positive regulation of canonical Wnt receptor signaling pathway
A/B=39-363 P negative regulation of interleukin-12 biosynthetic process
A/B=39-363 P response to copper ion
A/B=39-363 P apoptotic process
A/B=39-363 P negative regulation of cytokine production
A/B=39-363 P response to bacterium
A/B=39-363 P cellular response to interleukin-1
A/B=39-363 P response to oxidative stress
A/B=39-363 P transcription, DNA-dependent
A/B=39-363 P negative regulation of transcription from RNA polymerase II promoter
A/B=39-363 P anti-apoptosis
Sequences
Download file with secondary structure created by Stride  
1nfk.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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