General information
PDB ID 1NKP
Title CRYSTAL STRUCTURE OF MYC-MAX RECOGNIZING DNA
PDB header TRANSCRIPTION/DNA
Date 2003-01-03
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.8
Kind dna
Organism HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1nkp.pdb ABDE FGHJ 0
Biounits:
1nkp.pdb1.pdb AB FG 1
1nkp.pdb2.pdb DE HJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HLH Domain P01106_355-407 0.0000000000000013 1 No_clan A 902 954 FG  H-Bb H-Mj 
HLH Domain P61244_24-75 7.5e-19 1 No_clan B 203 254 FG  H-Bb H-Mj 
HLH Domain P01106_355-407 0.0000000000000011 1 No_clan D 502 554 HJ  H-Bb H-Mj 
HLH Domain P61244_24-75 2.2e-18 1 No_clan E 704 754 HJ  H-Bb H-Mj 
Myc-LZ Family P01106_408-434 0.000000000000044 1 No_clan A 955 984   
IncA Family 0.00014 0 No_clan B 203 283 FG
Myc-LZ Family P01106_408-434 0.0000000000068 1 No_clan D 555 581   
IncA Family 0.00013 0 No_clan E 705 783 HJ
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Myc proto-oncogene protein A N/A N/A FG  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein B N/A N/A FG  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Myc proto-oncogene protein D N/A N/A HJ  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein E N/A N/A HJ  H-Bb H-Mj 
GO terms
Protein chains: GO type: GO description:
A/D=353-434 C axon
A/D=353-434 C nuclear body
A/D=353-434 C nucleoplasm
A/D=353-434 C protein complex
A/D=353-434 C nucleolus
A/D=353-434 C spindle
A/D=353-434 F E-box binding
A/D=353-434 F double-stranded DNA binding
A/D=353-434 P response to gamma radiation
A/D=353-434 P positive regulation of DNA biosynthetic process
A/D=353-434 P oxygen transport
A/D=353-434 P fibroblast apoptotic process
A/D=353-434 P DNA-dependent transcription, initiation
A/D=353-434 P response to DNA damage stimulus
A/D=353-434 P induction of apoptosis by intracellular signals
A/D=353-434 P negative regulation of cell division
A/D=353-434 P positive regulation of response to DNA damage stimulus
A/D=353-434 P cell cycle arrest
A/D=353-434 P chromatin remodeling
A/D=353-434 P activation of pro-apoptotic gene products
A/D=353-434 P regulation of telomere maintenance
A/D=353-434 P positive regulation of epithelial cell proliferation
A/D=353-434 P positive regulation of transcription from RNA polymerase II promoter
A/D=353-434 P activation of cysteine-type endopeptidase activity involved in apoptotic process
A/D=353-434 P cellular iron ion homeostasis
A/D=353-434 P positive regulation of fibroblast proliferation
A/D=353-434 P protein processing
A/D=353-434 P negative regulation of stress-activated MAPK cascade
A/D=353-434 P canonical Wnt receptor signaling pathway
A/D=353-434 P MAPK cascade
A/D=353-434 P positive regulation of B cell apoptotic process
A/D=353-434 P positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
A/D=353-434 P cellular response to UV
A/D=353-434 P skeletal system morphogenesis
A/D=353-434 P middle ear morphogenesis
A/D=353-434 P pigmentation
A/D=353-434 P apoptotic DNA fragmentation
A/D=353-434 P positive regulation of metanephric cap mesenchymal cell proliferation
A/D=353-434 P negative regulation of survival gene product expression
A/D=353-434 P Notch signaling pathway
A/D=353-434 P negative regulation of G2 phase of mitotic cell cycle
A/D=353-434 P energy reserve metabolic process
A/D=353-434 P negative regulation of protein binding
A/D=353-434 P branching involved in ureteric bud morphogenesis
A/D=353-434 P detection of mechanical stimulus involved in sensory perception of sound
A/D=353-434 P negative regulation of fibroblast proliferation
A/D=353-434 P release of cytochrome c from mitochondria
A/D=353-434 P response to growth factor stimulus
A/D=353-434 P negative regulation of transcription from RNA polymerase II promoter
A/D=353-434 P negative regulation of apoptotic process
A/D=353-434 P cellular response to drug
A/D=353-434 P glucose metabolic process
A/D=353-434 P B cell apoptotic process
A/D=353-434 P response to alkaloid
A/D=353-434 P negative regulation of monocyte differentiation
B/E=23-102 C PML body
B/E=23-102 C MLL1 complex
B/E=23-102 C dendrite
B/E=23-102 C cytoplasm
B/E=23-102 F transcription coactivator activity
B/E=23-102 F sequence-specific DNA binding
B/E=23-102 F sequence-specific DNA binding transcription factor activity
B/E=23-102 P transcription from RNA polymerase II promoter
B/E=23-102 P retina development in camera-type eye
B/E=23-102 P cellular response to peptide hormone stimulus
B/E=23-102 P response to axon injury
B/E=23-102 P response to insulin stimulus
B/E=23-102 P response to organic nitrogen
B/E=23-102 P protein complex assembly
B/E=23-102 P negative regulation of gene expression
B/E=23-102 P neuron apoptotic process
B/E=23-102 P cellular response to starvation
Sequences
Download file with secondary structure created by Stride  
1nkp.pdb1.pdb:   [ download sequences in FASTA format ]
F (dna): 
Click "SHOW" for view sequence
G (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
1nkp.pdb2.pdb:   [ download sequences in FASTA format ]
H (dna): 
Click "SHOW" for view sequence
J (dna): 
Click "SHOW" for view sequence
D (protein): 
Click "SHOW" for view sequence
E (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2019

text