General information
PDB ID 1NVP
Title HUMAN TFIIA/TBP/DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 2003-02-04
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.1
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1nvp.pdb ABCD EF 0
Biounits:
1nvp.pdb1.pdb ABCD EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
TBP Domain P20226_162-244 1.2e-32 1 CL0407 A 162 244 EF  S-Bb S-Mn L-Bb L-Mn 
TBP Domain P20226_252-335 8.8e-32 1 CL0407 A 252 335 EF  S-Bb S-Mn L-Bb L-Mj L-Mn 
TFIIA_gamma_N Domain P52657_3-49 2e-23 1 No_clan D 3 49   
TFIIA_gamma_C Domain P52657_57-99 2.2e-23 1 No_clan D 52 99   
TFIIA Family P52655_13-51 2.1e-18 1 No_clan B 13 51   
TFIIA Family P52655_330-376 6e-35 1 No_clan C 330 376 F  S-Bb L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: TBP-like
    Superfamily: TATA-box binding protein-like
      Family: TATA-box binding protein (TBP), C-terminal domain
TATA-box binding protein (TBP), C-terminal domain A 159 252 EF  S-Bb S-Mn L-Bb L-Mn 
Class: Alpha and beta proteins (a+b)
  Fold: TBP-like
    Superfamily: TATA-box binding protein-like
      Family: TATA-box binding protein (TBP), C-terminal domain
TATA-box binding protein (TBP), C-terminal domain A 253 338 EF  S-Bb S-Mn L-Bb L-Mn 
Class: All alpha proteins
  Fold: Transcription factor IIA (TFIIA), alpha-helical domain
    Superfamily: Transcription factor IIA (TFIIA), alpha-helical domain
      Family: Transcription factor IIA (TFIIA), alpha-helical domain
Large chain TOA1, N-terminal domain B N/A N/A -
Class: All beta proteins
  Fold: Transcription factor IIA (TFIIA), beta-barrel domain
    Superfamily: Transcription factor IIA (TFIIA), beta-barrel domain
      Family: Transcription factor IIA (TFIIA), beta-barrel domain
Large chain TOA1, C-terminal domain C N/A N/A F  S-Bb L-Bb 
Class: All alpha proteins
  Fold: Transcription factor IIA (TFIIA), alpha-helical domain
    Superfamily: Transcription factor IIA (TFIIA), alpha-helical domain
      Family: Transcription factor IIA (TFIIA), alpha-helical domain
Small chain TOA2, N-terminal domain D 3 53 -
Class: All beta proteins
  Fold: Transcription factor IIA (TFIIA), beta-barrel domain
    Superfamily: Transcription factor IIA (TFIIA), beta-barrel domain
      Family: Transcription factor IIA (TFIIA), beta-barrel domain
Small chain TOA2, C-terminal domain D 54 99 -
GO terms
Protein chains: GO type: GO description:
A=159-339 C cytoplasm
A=159-339 C nuclear euchromatin
A=159-339 C female pronucleus
A=159-339 C male pronucleus
A=159-339 C transcription factor TFIID complex
A=159-339 F transcription regulatory region DNA binding
A=159-339 F sequence-specific DNA binding transcription factor activity
A=159-339 P spermatogenesis
A=159-339 P positive regulation of transcription, DNA-dependent
A=159-339 P transcription from RNA polymerase III promoter
A=159-339 P virus-host interaction
A=159-339 P cell death
B=2-58, C=303-376 C transcription factor TFIIA complex
B=2-58, C=303-376 F transcription coactivator activity
B=2-58, C=303-376 F DNA binding
B=2-58, C=303-376 P viral reproduction
B=2-58, C=303-376 P transcription elongation from RNA polymerase II promoter
B=2-58, C=303-376 P regulation of transcription, DNA-dependent
B=2-58, C=303-376 P transcription initiation from RNA polymerase II promoter
D=2-109 P positive regulation of transcription from RNA polymerase II promoter
D=2-109 P positive regulation of sequence-specific DNA binding transcription factor activity
D=2-109 P RNA polymerase II transcriptional preinitiation complex assembly
Sequences
Download file with secondary structure created by Stride  
1nvp.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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