General information
PDB ID 1OZJ
Title CRYSTAL STRUCTURE OF SMAD3-MH1 BOUND TO DNA AT 2.4 A RESOLUTION
PDB header TRANSCRIPTION/DNA
Date 2003-04-09
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.4
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1ozj.pdb AB CD 0
Biounits:
1ozj.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MH1 Domain P84022_31-131 7e-45 1 CL0263 A 31 131 CD  H-Bb S-Bb S-Mj L-Bb L-Mj 
MH1 Domain P84022_31-131 6.6e-45 1 CL0263 B 31 131 CD  S-Bb S-Mj L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: SMAD MH1 domain
    Superfamily: SMAD MH1 domain
      Family: SMAD MH1 domain
SMAD MH1 domain A N/A N/A CD  H-Bb S-Bb S-Mj L-Bb L-Mj 
Class: Alpha and beta proteins (a+b)
  Fold: SMAD MH1 domain
    Superfamily: SMAD MH1 domain
      Family: SMAD MH1 domain
SMAD MH1 domain B N/A N/A CD  S-Bb S-Mj L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=1-144 C cytosol
A/B=1-144 C SMAD protein complex
A/B=1-144 C nucleoplasm
A/B=1-144 C transcription factor complex
A/B=1-144 C nuclear inner membrane
A/B=1-144 C receptor complex
A/B=1-144 C plasma membrane
A/B=1-144 F double-stranded DNA binding
A/B=1-144 F zinc ion binding
A/B=1-144 F chromatin DNA binding
A/B=1-144 F transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
A/B=1-144 F sequence-specific DNA binding transcription factor activity
A/B=1-144 F core promoter proximal region sequence-specific DNA binding
A/B=1-144 P negative regulation of protein catabolic process
A/B=1-144 P in utero embryonic development
A/B=1-144 P paraxial mesoderm morphogenesis
A/B=1-144 P positive regulation of interleukin-1 beta production
A/B=1-144 P nodal signaling pathway
A/B=1-144 P induction of apoptosis
A/B=1-144 P immune response
A/B=1-144 P transforming growth factor beta receptor signaling pathway
A/B=1-144 P regulation of epithelial cell proliferation
A/B=1-144 P positive regulation of transforming growth factor beta3 production
A/B=1-144 P somitogenesis
A/B=1-144 P response to hypoxia
A/B=1-144 P heart looping
A/B=1-144 P cell cycle arrest
A/B=1-144 P negative regulation of mitotic cell cycle
A/B=1-144 P positive regulation of stress fiber assembly
A/B=1-144 P regulation of striated muscle tissue development
A/B=1-144 P positive regulation of catenin import into nucleus
A/B=1-144 P osteoblast development
A/B=1-144 P regulation of transforming growth factor beta receptor signaling pathway
A/B=1-144 P T cell activation
A/B=1-144 P positive regulation of bone mineralization
A/B=1-144 P positive regulation of canonical Wnt receptor signaling pathway
A/B=1-144 P embryonic foregut morphogenesis
A/B=1-144 P ureteric bud development
A/B=1-144 P negative regulation of inflammatory response
A/B=1-144 P release of cytochrome c from mitochondria
A/B=1-144 P endoderm development
A/B=1-144 P negative regulation of osteoblast differentiation
A/B=1-144 P cell-cell junction organization
A/B=1-144 P embryonic pattern specification
A/B=1-144 P positive regulation of epithelial to mesenchymal transition
A/B=1-144 P negative regulation of cell growth
A/B=1-144 P positive regulation of alkaline phosphatase activity
A/B=1-144 P liver development
A/B=1-144 P embryonic cranial skeleton morphogenesis
A/B=1-144 P regulation of binding
A/B=1-144 P immune system development
A/B=1-144 P positive regulation of transcription factor import into nucleus
A/B=1-144 P protein stabilization
A/B=1-144 P activation of pro-apoptotic gene products
A/B=1-144 P regulation of transforming growth factor beta2 production
A/B=1-144 P positive regulation of focal adhesion assembly
A/B=1-144 P developmental growth
A/B=1-144 P primary miRNA processing
A/B=1-144 P SMAD protein complex assembly
A/B=1-144 P pericardium development
A/B=1-144 P transport
A/B=1-144 P positive regulation of transcription from RNA polymerase II promoter
A/B=1-144 P positive regulation of cell migration
A/B=1-144 P regulation of immune response
A/B=1-144 P positive regulation of positive chemotaxis
A/B=1-144 P evasion of host defenses by virus
A/B=1-144 P positive regulation of chondrocyte differentiation
A/B=1-144 P transcription, DNA-dependent
A/B=1-144 P thyroid gland development
A/B=1-144 P negative regulation of transcription from RNA polymerase II promoter
A/B=1-144 P mesoderm formation
A/B=1-144 P negative regulation of apoptotic process
A/B=1-144 P negative regulation of protein phosphorylation
A/B=1-144 P activation of cysteine-type endopeptidase activity involved in apoptotic process
A/B=1-144 P negative regulation of osteoblast proliferation
A/B=1-144 P negative regulation of wound healing
A/B=1-144 P wound healing
A/B=1-144 P lens fiber cell differentiation
A/B=1-144 P transdifferentiation
Sequences
Download file with secondary structure created by Stride  
1ozj.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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