General information
PDB ID 1PUE
Title PU.1 ETS DOMAIN-DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 1996-07-08
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.1
Kind dna
Organism SYNTHETIC CONSTRUCT, MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1pue.pdb EF ABCD 0
Biounits:
1pue.pdb1.pdb E AB 1
1pue.pdb2.pdb F CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Ets Domain P17433_173-255 1.8e-24 1 CL0123 E 173 255 AB   
Ets Domain P17433_173-255 1.9e-24 1 CL0123 F 173 255 CD  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: ets domain
Transcription factor PU.1, residues 171-259 E N/A N/A AB  H-Bb H-Mj S-Bb L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: ets domain
Transcription factor PU.1, residues 171-259 F N/A N/A CD  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
E/F=171-259 C nuclear chromatin
E/F=171-259 C transcription factor complex
E/F=171-259 F RNA polymerase II distal enhancer sequence-specific DNA binding
E/F=171-259 F core promoter binding
E/F=171-259 F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
E/F=171-259 F RNA binding
E/F=171-259 P negative regulation of transcription, DNA-dependent
E/F=171-259 P myeloid dendritic cell differentiation
E/F=171-259 P granulocyte differentiation
E/F=171-259 P induction of apoptosis
E/F=171-259 P regulation of erythrocyte differentiation
E/F=171-259 P macrophage differentiation
E/F=171-259 P negative regulation of histone H4 acetylation
E/F=171-259 P anatomical structure regression
E/F=171-259 P erythrocyte differentiation
E/F=171-259 P lymphocyte differentiation
E/F=171-259 P lymphoid progenitor cell differentiation
E/F=171-259 P histone H3 acetylation
E/F=171-259 P vasculature development
E/F=171-259 P somatic stem cell maintenance
E/F=171-259 P negative regulation of MHC class II biosynthetic process
E/F=171-259 P negative regulation of gene expression, epigenetic
E/F=171-259 P hypermethylation of CpG island
Sequences
Download file with secondary structure created by Stride  
1pue.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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E (protein): 
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1pue.pdb2.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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F (protein): 
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