General information
PDB ID 1PZU
Title AN ASYMMETRIC NFAT1-RHR HOMODIMER ON A PSEUDO-PALINDROMIC, KAPPA-B SITE
PDB header TRANSCRIPTION/DNA
Date 2003-07-14
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.1
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1pzu.pdb BDHILM XYVZTW 0
Biounits:
1pzu.pdb1.pdb BD TW 1
1pzu.pdb2.pdb HI VZ 1
1pzu.pdb3.pdb LM XY 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 B 579 678 W  L-Bb 
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 B 410 570 TW  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 D 579 678   
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 D 410 570 TW  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 H 579 678   
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 H 410 570 VZ  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 I 579 678 V  L-Bb 
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 I 410 570 VZ  H-Bb S-Bb L-Bb L-Mj L-Mn 
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 L 579 678   
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 L 410 570 XY  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6e-26 1 CL0159 M 579 678   
RHD_DNA_bind Domain Q13469_410-570 4.2e-23 1 CL0073 M 410 570 XY  H-Bb S-Bb L-Bb L-Mj L-Mn 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) B 576 678 W  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain B 399 571 TW  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) D 576 678 -
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain D 399 571 TW  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) H 576 678 -
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain H 399 571 VZ  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) I 576 678 V  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain I 399 571 VZ  H-Bb S-Bb L-Bb L-Mj L-Mn 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) L 576 678 -
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain L 399 571 XY  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) M 576 678 -
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain M 399 571 XY  H-Bb S-Bb L-Bb L-Mj L-Mn 
GO terms
Protein chains: GO type: GO description:
B/D/H/I/L/M=396-678 C actin cytoskeleton
B/D/H/I/L/M=396-678 C cytosol
B/D/H/I/L/M=396-678 C ribonucleoprotein complex
B/D/H/I/L/M=396-678 C plasma membrane
B/D/H/I/L/M=396-678 C nucleus
B/D/H/I/L/M=396-678 F sequence-specific DNA binding transcription factor activity
B/D/H/I/L/M=396-678 F DNA binding
B/D/H/I/L/M=396-678 F transcription regulatory region DNA binding
B/D/H/I/L/M=396-678 F sequence-specific DNA binding
B/D/H/I/L/M=396-678 P B cell receptor signaling pathway
B/D/H/I/L/M=396-678 P positive regulation of transcription from RNA polymerase II promoter
B/D/H/I/L/M=396-678 P transcription, DNA-dependent
B/D/H/I/L/M=396-678 P cytokine production
B/D/H/I/L/M=396-678 P response to DNA damage stimulus
B/D/H/I/L/M=396-678 P positive regulation of B cell proliferation
B/D/H/I/L/M=396-678 P response to drug
B/D/H/I/L/M=396-678 P positive regulation of transcription, DNA-dependent
Sequences
Download file with secondary structure created by Stride  
1pzu.pdb1.pdb:   [ download sequences in FASTA format ]
T (dna): 
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W (dna): 
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B (protein): 
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D (protein): 
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1pzu.pdb2.pdb:   [ download sequences in FASTA format ]
V (dna): 
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Z (dna): 
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H (protein): 
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I (protein): 
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1pzu.pdb3.pdb:   [ download sequences in FASTA format ]
X (dna): 
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Y (dna): 
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L (protein): 
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M (protein): 
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