General information
PDB ID 1R4I
Title CRYSTAL STRUCTURE OF ANDROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO A DIRECT REPEAT RESPONSE ELEMENT
PDB header TRANSCRIPTION/DNA
Date 2003-10-06
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.1
Kind dna
Organism RATTUS NORVEGICUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1r4i.pdb AB CD 0
Biounits:
1r4i.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P15207_540-609 1.4e-29 1 CL0167 A 540 609 CD  H-Bb H-Mj S-Bb L-Bb 
zf-C4 Domain P15207_540-609 1.2e-29 1 CL0167 B 540 609 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Androgen receptor A N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Androgen receptor B N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=533-637 C nuclear chromatin
A/B=533-637 C dendrite
A/B=533-637 C cytoplasm
A/B=533-637 C axon
A/B=533-637 F zinc ion binding
A/B=533-637 F androgen binding
A/B=533-637 F transcription regulatory region DNA binding
A/B=533-637 F androgen receptor activity
A/B=533-637 F sequence-specific DNA binding
A/B=533-637 F chromatin binding
A/B=533-637 P organ formation
A/B=533-637 P regulation of developmental growth
A/B=533-637 P regulation of catalytic activity
A/B=533-637 P regulation of prostatic bud formation
A/B=533-637 P negative regulation of apoptotic process
A/B=533-637 P in utero embryonic development
A/B=533-637 P mammary gland alveolus development
A/B=533-637 P prostate gland growth
A/B=533-637 P positive regulation of transcription from RNA polymerase III promoter
A/B=533-637 P negative regulation of epithelial cell proliferation
A/B=533-637 P regulation of establishment of protein localization in plasma membrane
A/B=533-637 P male somatic sex determination
A/B=533-637 P lateral sprouting involved in mammary gland duct morphogenesis
A/B=533-637 P positive regulation of integrin biosynthetic process
A/B=533-637 P positive regulation of phosphorylation
A/B=533-637 P positive regulation of insulin-like growth factor receptor signaling pathway
A/B=533-637 P negative regulation of integrin biosynthetic process
A/B=533-637 P positive regulation of MAPK cascade
A/B=533-637 P epithelial cell differentiation involved in prostate gland development
A/B=533-637 P prostate gland epithelium morphogenesis
A/B=533-637 P response to insulin stimulus
A/B=533-637 P positive regulation of NF-kappaB transcription factor activity
A/B=533-637 P male gonad development
A/B=533-637 P tertiary branching involved in mammary gland duct morphogenesis
A/B=533-637 P morphogenesis of an epithelial fold
A/B=533-637 P positive regulation of transcription from RNA polymerase II promoter
A/B=533-637 P male genitalia morphogenesis
A/B=533-637 P positive regulation of cell proliferation
A/B=533-637 P activation of prostate induction by androgen receptor signaling pathway
A/B=533-637 P male sex differentiation
A/B=533-637 P positive regulation of intracellular estrogen receptor signaling pathway
Sequences
Download file with secondary structure created by Stride  
1r4i.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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