General information
PDB ID 1R4R
Title CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA
PDB header TRANSCRIPTION/DNA
Date 2003-10-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 3
Kind dna
Organism RATTUS NORVEGICUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1r4r.pdb AB CD 0
Biounits:
1r4r.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P06536_438-507 3.3e-30 1 CL0167 A 438 507 CD  H-Bb H-Mj S-Bb L-Bb 
zf-C4 Domain P06536_438-507 4e-30 1 CL0167 B 438 507 CD  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Glucocorticoid receptor DNA-binding domain A N/A N/A CD  H-Bb H-Mj L-Bb 
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Glucocorticoid receptor DNA-binding domain B N/A N/A CD  H-Bb H-Mj S-Bb S-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=440-525 C postsynaptic density
A/B=440-525 C membrane
A/B=440-525 C synaptosome
A/B=440-525 C cytoplasm
A/B=440-525 C cytosol
A/B=440-525 C protein complex
A/B=440-525 C nucleus
A/B=440-525 F double-stranded DNA binding
A/B=440-525 F transcription coactivator activity
A/B=440-525 F steroid binding
A/B=440-525 F RNA polymerase II regulatory region DNA binding
A/B=440-525 F sequence-specific DNA binding
A/B=440-525 F hormone binding
A/B=440-525 F glucocorticoid receptor activity
A/B=440-525 F chromatin binding
A/B=440-525 F sequence-specific DNA binding transcription factor activity
A/B=440-525 F zinc ion binding
A/B=440-525 P regulation of glucocorticoid biosynthetic process
A/B=440-525 P response to activity
A/B=440-525 P negative regulation of transforming growth factor beta receptor signaling pathway
A/B=440-525 P response to electrical stimulus
A/B=440-525 P mammary gland duct morphogenesis
A/B=440-525 P androgen metabolic process
A/B=440-525 P response to corticosterone stimulus
A/B=440-525 P cellular response to dexamethasone stimulus
A/B=440-525 P positive regulation of glutamate secretion
A/B=440-525 P cellular response to magnesium ion
A/B=440-525 P chromatin-mediated maintenance of transcription
A/B=440-525 P brain development
A/B=440-525 P regulation of glucose metabolic process
A/B=440-525 P response to insulin stimulus
A/B=440-525 P positive regulation of neuron apoptotic process
A/B=440-525 P glucocorticoid metabolic process
A/B=440-525 P response to radiation
A/B=440-525 P lung development
A/B=440-525 P circadian rhythm
A/B=440-525 P muscle atrophy
A/B=440-525 P response to mercury ion
A/B=440-525 P response to arsenic-containing substance
A/B=440-525 P aging
A/B=440-525 P positive regulation of transcription from RNA polymerase II promoter
A/B=440-525 P response to inactivity
A/B=440-525 P response to calcium ion
A/B=440-525 P regulation of gluconeogenesis
A/B=440-525 P adrenal gland development
A/B=440-525 P positive regulation of glucocorticoid receptor signaling pathway
A/B=440-525 P negative regulation of vascular permeability
A/B=440-525 P transcription, DNA-dependent
A/B=440-525 P regulation of cell proliferation
A/B=440-525 P anti-apoptosis
Sequences
Download file with secondary structure created by Stride  
1r4r.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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