General information
PDB ID 1SRS
Title SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
PDB header TRANSCRIPTION/DNA
Date 1995-07-28
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1srs.pdb AB WC 0
Biounits:
1srs.pdb1.pdb AB WC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
SRF-TF Domain P11831_150-197 4.4e-21 1 No_clan A 150 197 C   
SRF-TF Domain P11831_150-197 3.9e-21 1 No_clan B 150 197 CW   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Serum response factor (SRF) core A N/A N/A CW  L-Bb 
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Serum response factor (SRF) core B N/A N/A CW  H-Bb H-Mj L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
A/B=132-223 C endoplasmic reticulum
A/B=132-223 C nucleus
A/B=132-223 C nuclear chromatin
A/B=132-223 F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
A/B=132-223 F RNA polymerase II transcription factor binding transcription factor activity
A/B=132-223 F sequence-specific DNA binding
A/B=132-223 F serum response element binding
A/B=132-223 F chromatin DNA binding
A/B=132-223 F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
A/B=132-223 P primitive streak formation
A/B=132-223 P neuron migration
A/B=132-223 P muscle cell homeostasis
A/B=132-223 P patterning of blood vessels
A/B=132-223 P eyelid development in camera-type eye
A/B=132-223 P dorsal aorta morphogenesis
A/B=132-223 P megakaryocyte development
A/B=132-223 P epithelial structure maintenance
A/B=132-223 P erythrocyte development
A/B=132-223 P negative regulation of cell migration
A/B=132-223 P contractile actin filament bundle assembly
A/B=132-223 P cardiac vascular smooth muscle cell differentiation
A/B=132-223 P positive thymic T cell selection
A/B=132-223 P tangential migration from the subventricular zone to the olfactory bulb
A/B=132-223 P regulation of smooth muscle cell differentiation
A/B=132-223 P negative regulation of cell proliferation
A/B=132-223 P positive regulation of transcription via serum response element binding
A/B=132-223 P response to toxin
A/B=132-223 P trophectodermal cell differentiation
A/B=132-223 P positive regulation of smooth muscle contraction
A/B=132-223 P mesoderm formation
A/B=132-223 P skin morphogenesis
A/B=132-223 P heart looping
A/B=132-223 P tight junction assembly
A/B=132-223 P neuron projection development
A/B=132-223 P response to cytokine stimulus
A/B=132-223 P platelet formation
A/B=132-223 P associative learning
A/B=132-223 P hippocampus development
A/B=132-223 P heart trabecula formation
A/B=132-223 P positive regulation of cell differentiation
A/B=132-223 P positive regulation of transcription initiation from RNA polymerase II promoter
A/B=132-223 P stress fiber assembly
A/B=132-223 P long-term memory
A/B=132-223 P cell-matrix adhesion
A/B=132-223 P platelet activation
A/B=132-223 P cardiac myofibril assembly
A/B=132-223 P morphogenesis of an epithelial sheet
A/B=132-223 P sarcomere organization
A/B=132-223 P angiogenesis involved in wound healing
A/B=132-223 P developmental growth
A/B=132-223 P response to hormone stimulus
A/B=132-223 P hemopoietic stem cell differentiation
A/B=132-223 P regulation of water loss via skin
A/B=132-223 P cell migration involved in sprouting angiogenesis
A/B=132-223 P regulation of cell adhesion
A/B=132-223 P neuron development
A/B=132-223 P epithelial cell-cell adhesion
A/B=132-223 P positive regulation of filopodium assembly
A/B=132-223 P cellular senescence
A/B=132-223 P long term synaptic depression
Sequences
Download file with secondary structure created by Stride  
1srs.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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W (dna): 
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A (protein): 
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B (protein): 
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