General information
PDB ID 1T05
Title HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO TEMPLATE-PRIMER WITH TENOFOVIR-DIPHOSPHATE BOUND AS THE INCOMING NUCLEOTIDE SUBSTRATE
PDB header TRANSFERASE/DNA
Date 2004-04-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 3
Kind dna
Organism HUMAN IMMUNODEFICIENCY VIRUS 1
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1t05.pdb AB TP 0
Biounits:
1t05.pdb1.pdb AB TP 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P03366_917-1018 2.2e-59 1 No_clan A 318 419   
RNase_H Domain P03366_1035-1153 2.4e-28 1 CL0219 A 436 554 P  H-Bb 
RVT_thumb Domain P03366_840-903 3.6e-18 1 No_clan A 241 304 TP  L-Bb 
RVT_connect Domain P04585_905-1006 1.3e-59 1 No_clan B 318 419 P  H-Bb 
RVT_thumb Domain P04585_828-891 3.8e-20 1 No_clan B 241 304   
RVT_1 Family P03366_662-833 1.4e-34 1 CL0027 A 63 234 PT   
RVT_1 Family P04585_650-821 4e-33 1 CL0027 B 63 253   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a/b)
  Fold: Ribonuclease H-like motif
    Superfamily: Ribonuclease H-like
      Family: Ribonuclease H
HIV RNase H (Domain of reverse transcriptase) A 430 554 P -
Class: Multi-domain proteins (alpha and beta)
  Fold: DNA/RNA polymerases
    Superfamily: DNA/RNA polymerases
      Family: Reverse transcriptase
HIV-1 reverse transcriptase A 1 429 PT -
Class: Multi-domain proteins (alpha and beta)
  Fold: DNA/RNA polymerases
    Superfamily: DNA/RNA polymerases
      Family: Reverse transcriptase
HIV-1 reverse transcriptase B N/A N/A P -
GO terms
Protein chains: GO type: GO description:
B=588-1016 C nucleoplasm
B=588-1016 C viral capsid
B=588-1016 C cytosol
B=588-1016 C host cell plasma membrane
B=588-1016 C membrane
B=588-1016 C host cell nucleus
B=588-1016 C host cell cytoplasm
B=588-1016 F exoribonuclease H activity
B=588-1016 F DNA-directed DNA polymerase activity
B=588-1016 F zinc ion binding
B=588-1016 F RNA-directed DNA polymerase activity
B=588-1016 F aspartic-type endopeptidase activity
B=588-1016 F ribonuclease H activity
B=588-1016 F RNA binding
B=588-1016 F DNA binding
B=588-1016 F structural molecule activity
B=588-1016 P uncoating of virus
B=588-1016 P modulation by virus of host apoptosis
B=588-1016 P viral procapsid maturation
B=588-1016 P proteolysis
B=588-1016 P entry into host cell
B=588-1016 P provirus integration
B=588-1016 P nucleic acid phosphodiester bond hydrolysis
B=588-1016 P RNA-dependent DNA replication
Sequences
Download file with secondary structure created by Stride  
1t05.pdb1.pdb:   [ download sequences in FASTA format ]
P (dna): 
Click "SHOW" for view sequence
T (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2019

text