General information
PDB ID 1YO5
Title ANALYSIS OF THE 2.0A CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX OF HUMAN PDEF ETS DOMAIN BOUND TO THE PROSTATE SPECIFIC ANTIGEN REGULATORY SITE
PDB header TRANSCRIPTION/DNA
Date 2005-01-26
Experimental method X-RAY DIFFRACTION
Resolution (A) 2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1yo5.pdb C AB 0
Biounits:
1yo5.pdb1.pdb C AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Ets Domain O95238_250-332 1.2e-35 1 CL0123 C 250 332 AB  H-Bb H-Mj S-Bb L-Bb L-Mn 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: ets domain
Sam pointed domain containing ets transcription SPDEF C 247 334 AB  H-Bb H-Mj S-Bb L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
C=247-335 C nucleus
C=247-335 F sequence-specific DNA binding
C=247-335 F sequence-specific DNA binding transcription factor activity
C=247-335 P positive regulation of cell fate commitment
C=247-335 P intestinal epithelial cell development
C=247-335 P lung goblet cell differentiation
C=247-335 P negative regulation of transcription from RNA polymerase II promoter
C=247-335 P negative regulation of cell fate commitment
C=247-335 P negative regulation of survival gene product expression
C=247-335 P positive regulation of transcription from RNA polymerase II promoter
C=247-335 P multicellular organismal development
C=247-335 P transcription, DNA-dependent
Sequences
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1yo5.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (protein): 
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