General information
PDB ID 2AZX
Title CHARGED AND UNCHARGED TRNAS ADOPT DISTINCT CONFORMATIONS WHEN COMPLEXED WITH HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
PDB header LIGASE/RNA
Date 2005-09-12
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.8
Kind rna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2azx.pdb AB CD 0
Biounits:
2azx.pdb1.pdb AD CB 0
2azx.pdb2.pdb BC DA 0
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
tRNA-synt_1b Family P23381_151-443 2e-13 1 CL0039 A 151 442 BC   
tRNA-synt_1b Family P23381_151-443 2e-13 1 CL0039 B 151 442 D   
tRNA-synt_1b Family 2e-13 1 CL0039 C 151 442 A
tRNA-synt_1b Family 2e-13 1 CL0039 D 151 442 BC
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a/b)
  Fold: Adenine nucleotide alpha hydrolase-like
    Superfamily: Nucleotidylyl transferase
      Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain
Tryptophanyl-tRNA synthetase (TrpRS) A 82 468 BC -
Class: Alpha and beta proteins (a/b)
  Fold: Adenine nucleotide alpha hydrolase-like
    Superfamily: Nucleotidylyl transferase
      Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain
Tryptophanyl-tRNA synthetase (TrpRS) B 82 468 D -
GO terms
Protein chains: GO type: GO description:
A/B=1-471 C cytosol
A/B=1-471 F tryptophan-tRNA ligase activity
A/B=1-471 F ATP binding
A/B=1-471 P tryptophanyl-tRNA aminoacylation
A/B=1-471 P negative regulation of cell proliferation
A/B=1-471 P regulation of angiogenesis
A/B=1-471 P angiogenesis
Sequences
Download file with secondary structure created by Stride  
2azx.pdb1.pdb:   [ download sequences in FASTA format ]
A (protein): 
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D (protein): 
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B (rna): 
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C (rna): 
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2azx.pdb2.pdb:   [ download sequences in FASTA format ]
B (protein): 
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C (protein): 
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A (rna): 
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D (rna): 
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