General information
PDB ID 2CV5
Title CRYSTAL STRUCTURE OF HUMAN NUCLEOSOME CORE PARTICLE
PDB header STRUCTURAL PROTEIN/DNA
Date 2005-05-31
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.5
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2cv5.pdb ABCDEFGH IJ 0
Biounits:
2cv5.pdb1.pdb ABCDEFGH IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P68431_39-132 9.1e-47 1 CL0012 A 38 131 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
CENP-T_C Domain P62805_26-99 0.0000000085 1 CL0012 B 26 98 IJ  H-Bb S-Bb L-Bb 
Histone Domain P04908_16-91 2.1e-16 1 CL0012 C 11 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain O60814_32-102 4.1e-22 1 CL0012 D 27 98 IJ  H-Bb H-Mj S-Bb L-Bb 
Histone Domain P68431_39-132 4.3e-47 1 CL0012 E 37 131 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
CENP-T_C Domain P62805_19-99 0.00000001 1 CL0012 F 24 98 IJ  H-Bb S-Bb L-Bb 
Histone Domain P04908_16-91 4.2e-16 1 CL0012 G 15 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain O60814_32-102 9.9e-22 1 CL0012 H 28 98 IJ  H-Bb S-Bb L-Bb 
Histone_H2A_C Family P04908_92-119 1.5e-17 1 No_clan C 91 118   
Histone_H2A_C Family P04908_92-119 1.4e-17 1 No_clan G 91 118   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H3 A 38 134 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H4 B 25 102 IJ  H-Bb S-Bb L-Bb 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H2A C 11 118 IJ  H-Bb S-Bb L-Bb 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H2B D 27 122 IJ  H-Bb H-Mj S-Bb L-Bb 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H3 E 38 135 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H4 F 24 102 IJ  H-Bb H-Mj S-Bb L-Bb 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H2A G 15 118 IJ  H-Bb S-Bb L-Bb 
Class: All alpha proteins
  Fold: Histone-fold
    Superfamily: Histone-fold
      Family: Nucleosome core histones
Histone H2B H 28 121 IJ  H-Bb S-Bb L-Bb 
GO terms
Protein chains: GO type: GO description:
A/E=1-136 C nucleoplasm
A/E=1-136 C extracellular region
A/E=1-136 P blood coagulation
A/E=1-136 P regulation of gene silencing
A/E=1-136 P S phase
B/F=1-103 P telomere maintenance
B/F=1-103 P negative regulation of megakaryocyte differentiation
B/F=1-103 P CenH3-containing nucleosome assembly at centromere
B/F=1-103 P phosphatidylinositol-mediated signaling
C/G=1-130 C nucleus
C/G=1-130 C nucleosome
C/G=1-130 F DNA binding
C/G=1-130 P nucleosome assembly
D/H=1-126 P defense response to bacterium
Sequences
Download file with secondary structure created by Stride  
2cv5.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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