General information
PDB ID 2E43
Title CRYSTAL STRUCTURE OF C/EBPBETA BZIP HOMODIMER K269A MUTANT BOUND TO A HIGH AFFINITY DNA FRAGMENT
PDB header TRANSCRIPTION/DNA
Date 2006-12-01
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.1
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2e43.pdb AB CD 0
Biounits:
2e43.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
bZIP_2 Family P17676_270-323 4e-19 1 CL0018 A 271 323 CD  H-Bb H-Mj 
bZIP_2 Family P17676_270-323 4.4e-19 1 CL0018 B 271 323 CD  H-Bb H-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Coiled coil proteins
  Fold: Parallel coiled-coil
    Superfamily: Leucine zipper domain
      Family: Leucine zipper domain
C/ebp beta A 271 332 CD  H-Bb H-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=259-336 C nuclear chromatin
A/B=259-336 C cytoplasm
A/B=259-336 C nucleus
A/B=259-336 C nuclear matrix
A/B=259-336 F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
A/B=259-336 F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
A/B=259-336 F DNA binding
A/B=259-336 F sequence-specific DNA binding
A/B=259-336 P anti-apoptosis
A/B=259-336 P regulation of interleukin-6 biosynthetic process
A/B=259-336 P embryonic placenta development
A/B=259-336 P negative regulation of transcription, DNA-dependent
A/B=259-336 P acute-phase response
A/B=259-336 P mammary gland epithelial cell differentiation
A/B=259-336 P immune response
A/B=259-336 P cellular response to amino acid stimulus
A/B=259-336 P positive regulation of osteoblast differentiation
A/B=259-336 P neuron differentiation
A/B=259-336 P induction of apoptosis
A/B=259-336 P response to lipopolysaccharide
A/B=259-336 P brown fat cell differentiation
A/B=259-336 P mammary gland epithelial cell proliferation
Sequences
Download file with secondary structure created by Stride  
2e43.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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