General information
PDB ID 2GLI
Title FIVE-FINGER GLI/DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 1993-11-09
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2gli.pdb A CD 0
Biounits:
2gli.pdb1.pdb A CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-H2C2_2 Domain 0.00000047 0 CL0361 A 186 213 C
zf-H2C2_2 Domain 0.0000019 0 CL0361 A 156 183 D
FOXP-CC Domain 0.000011 0 No_clan A 103 137
zf-C2H2 Domain P08151_362-387 0.000019 1 CL0361 A 231 256 CD  H-Bb H-Mj S-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
Five-finger GLI1 A 103 134 -
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
Five-finger GLI1 A 135 167 DC  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
Five-finger GLI1 A 168 197 DC  L-Bb 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
Five-finger GLI1 A 198 228 CD  H-Bb H-Mj S-Bb 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
Five-finger GLI1 A 229 257 CD  H-Bb H-Mj S-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
A=234-388 C nucleus
A=234-388 C cytosol
A=234-388 C cilium
A=234-388 F transcription regulatory region DNA binding
A=234-388 F chromatin binding
A=234-388 F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
A=234-388 F zinc ion binding
A=234-388 P positive regulation of cell proliferation
A=234-388 P smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
A=234-388 P positive regulation of transcription from RNA polymerase II promoter
A=234-388 P smoothened signaling pathway
A=234-388 P positive regulation of smoothened signaling pathway
A=234-388 P cerebellar cortex morphogenesis
A=234-388 P negative regulation of canonical Wnt receptor signaling pathway
A=234-388 P digestive tract morphogenesis
A=234-388 P ventral midline development
A=234-388 P positive regulation of DNA replication
A=234-388 P osteoblast differentiation
A=234-388 P lung development
A=234-388 P spermatogenesis
A=234-388 P epidermal cell differentiation
A=234-388 P proximal/distal pattern formation
A=234-388 P pituitary gland development
A=234-388 P notochord regression
A=234-388 P dorsal/ventral pattern formation
Sequences
Download file with secondary structure created by Stride  
2gli.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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