General information
PDB ID 2NTC
Title CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN ORIGIN BINDING DOMAIN WITH DNA
PDB header DNA BINDING PROTEIN/DNA
Date 2006-11-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.4
Kind dna
Organism SIMIAN VIRUS 40
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CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2ntc.pdb AB WC 0
Biounits:
2ntc.pdb1.pdb AB WC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
T_Ag_DNA_bind Domain Q98ZP7_136-229 5.5e-39 1 CL0169 A 136 229 CW  H-Bb S-Bb S-Mj L-Bb L-Mj 
T_Ag_DNA_bind Domain Q98ZP7_136-229 5.4e-39 1 CL0169 B 136 229 CW  H-Bb S-Bb S-Mj L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: Origin of replication-binding domain, RBD-like
    Superfamily: Origin of replication-binding domain, RBD-like
      Family: The origin DNA-binding domain of SV40 T-antigen
The origin DNA-binding domain of SV40 T-antigen A 132 256 CW -
Class: Alpha and beta proteins (a+b)
  Fold: Origin of replication-binding domain, RBD-like
    Superfamily: Origin of replication-binding domain, RBD-like
      Family: The origin DNA-binding domain of SV40 T-antigen
The origin DNA-binding domain of SV40 T-antigen B 133 256 CW -
GO terms
Protein chains: GO type: GO description:
A/B=131-260 C host cell nucleus
A/B=131-260 F helicase activity
A/B=131-260 F metal ion binding
A/B=131-260 F DNA replication origin binding
A/B=131-260 F ATP binding
A/B=131-260 P modulation by virus of host cell cycle
A/B=131-260 P suppression by virus of host type I interferon-mediated signaling pathway
A/B=131-260 P suppression by virus of host JAK1 activity
A/B=131-260 P DNA replication
A/B=131-260 P regulation of transcription, DNA-dependent
A/B=131-260 P transcription, DNA-dependent
A/B=131-260 P suppression by virus of tyrosine phosphorylation of host STAT protein
Sequences
Download file with secondary structure created by Stride  
2ntc.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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W (dna): 
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A (protein): 
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B (protein): 
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