General information
PDB ID 2O93
Title CRYSTAL STRUCTURE OF NFAT BOUND TO THE HIV-1 LTR TANDEM KAPPAB ENHANCER ELEMENT
PDB header TRANSCRIPTION/DNA
Date 2006-12-13
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.05
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2o93.pdb LMO AB 0
Biounits:
2o93.pdb1.pdb LMO AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RHD_dimer Domain Q13469_579-678 6.5e-26 1 CL0159 L 579 678 A  L-Bb 
RHD_DNA_bind Domain Q13469_410-570 4.7e-23 1 CL0073 L 410 570 AB  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6.4e-26 1 CL0159 M 579 678   
RHD_DNA_bind Domain Q13469_410-570 4.7e-23 1 CL0073 M 410 570 AB  H-Bb S-Bb L-Bb L-Mj 
RHD_dimer Domain Q13469_579-678 6.5e-26 1 CL0159 O 579 678 A  L-Bb 
RHD_DNA_bind Domain Q13469_410-570 4.7e-23 1 CL0073 O 410 570 AB  H-Bb S-Bb L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) L 576 678 A  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain L 393 575 AB  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) M 576 678 -
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain M 395 575 AB  H-Bb S-Bb L-Bb L-Mj 
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
T-cell transcription factor NFAT1 (NFATC2) O 576 678 A  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
T-cell transcription factor NFAT1 (NFATC), DNA-binding domain O 393 575 AB  H-Bb H-Mj S-Bb L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
L/M/O=396-678 C cytosol
L/M/O=396-678 C actin cytoskeleton
L/M/O=396-678 C plasma membrane
L/M/O=396-678 C ribonucleoprotein complex
L/M/O=396-678 C nucleus
L/M/O=396-678 F DNA binding
L/M/O=396-678 F sequence-specific DNA binding
L/M/O=396-678 F sequence-specific DNA binding transcription factor activity
L/M/O=396-678 F transcription regulatory region DNA binding
L/M/O=396-678 P positive regulation of transcription, DNA-dependent
L/M/O=396-678 P transcription, DNA-dependent
L/M/O=396-678 P positive regulation of transcription from RNA polymerase II promoter
L/M/O=396-678 P B cell receptor signaling pathway
L/M/O=396-678 P positive regulation of B cell proliferation
L/M/O=396-678 P response to DNA damage stimulus
L/M/O=396-678 P response to drug
L/M/O=396-678 P cytokine production
Sequences
Download file with secondary structure created by Stride  
2o93.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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L (protein): 
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M (protein): 
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O (protein): 
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