General information
PDB ID 2V2T
Title X-RAY STRUCTURE OF A NF-KB P50-RELB-DNA COMPLEX
PDB header TRANSCRIPTION
Date 2007-06-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.05
Kind dna
Organism MUS MUSCULUS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2v2t.pdb AB CD 0
Biounits:
2v2t.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RHD_DNA_bind Domain Q04863_105-273 1.7e-63 1 CL0073 A 105 273 CD  H-Bb H-Mj S-Bb S-Mj L-Bb L-Mj 
RHD_dimer Domain Q04863_282-378 6.2e-38 1 CL0159 A 282 378 C  L-Bb 
RHD_DNA_bind Domain P25799_42-240 7.3e-74 1 CL0073 B 42 240 CD  H-Bb H-Mj L-Bb L-Mj 
RHD_dimer Domain P25799_249-350 5.5e-42 1 CL0159 B 249 350 D  L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: Immunoglobulin-like beta-sandwich
    Superfamily: E set domains
      Family: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
p50 subunit of NF-kappa B transcription factor B 248 350 D  L-Bb 
Class: All beta proteins
  Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
    Superfamily: p53-like transcription factors
      Family: Rel/Dorsal transcription factors, DNA-binding domain
p50 subunit of NF-kappa B (NFKB), N-terminal domain B 39 247 CD  H-Bb H-Mj L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
A=91-378 C microtubule organizing center
A=91-378 F DNA binding
A=91-378 P T-helper 1 cell differentiation
A=91-378 P myeloid dendritic cell differentiation
A=91-378 P antigen processing and presentation
A=91-378 P positive regulation of gene expression
B=38-363 C protein complex
B=38-363 C nucleus
B=38-363 C cytosol
B=38-363 C mitochondrion
B=38-363 F nucleic acid binding transcription factor activity
B=38-363 F sequence-specific DNA binding
B=38-363 F transcription regulatory region sequence-specific DNA binding
B=38-363 F double-stranded DNA binding
B=38-363 F regulatory region DNA binding
B=38-363 F sequence-specific DNA binding transcription factor activity
B=38-363 P cellular response to interleukin-1
B=38-363 P response to copper ion
B=38-363 P positive regulation of canonical Wnt receptor signaling pathway
B=38-363 P response to bacterium
B=38-363 P negative regulation of transcription from RNA polymerase II promoter
B=38-363 P positive regulation of hyaluronan biosynthetic process
B=38-363 P apoptotic process
B=38-363 P signal transduction
B=38-363 P response to oxidative stress
B=38-363 P positive regulation of transcription from RNA polymerase II promoter
B=38-363 P transcription, DNA-dependent
B=38-363 P lymph node development
B=38-363 P negative regulation of cytokine production
B=38-363 P anti-apoptosis
B=38-363 P cellular response to mechanical stimulus
B=38-363 P negative regulation of calcidiol 1-monooxygenase activity
B=38-363 P negative regulation of interleukin-12 biosynthetic process
Sequences
Download file with secondary structure created by Stride  
2v2t.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
Click "SHOW" for view sequence
D (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2019

text