General information
PDB ID 3PT6
Title CRYSTAL STRUCTURE OF MOUSE DNMT1(650-1602) IN COMPLEX WITH DNA
PDB header TRANSFERASE/DNA
Date 2010-12-02
Experimental method X-RAY DIFFRACTION
Resolution (A) 3
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3pt6.pdb AB CDIJ 0
Biounits:
3pt6.pdb1.pdb A CI 1
3pt6.pdb2.pdb B DJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DNA_methylase Domain P13864_1142-1596 1.7e-47 1 CL0063 A 1142 1596 CI  H-Bb L-Bb 
BAH Domain P13864_935-1103 6.3e-22 1 No_clan A 935 1103   
BAH Domain P13864_758-884 5e-20 1 No_clan A 758 884   
zf-CXXC Domain P13864_651-694 4.8e-14 1 No_clan A 651 694 CI  L-Bb L-Mj 
DNA_methylase Domain P13864_1142-1596 1.7e-47 1 CL0063 B 1142 1596 D  H-Bb L-Bb 
BAH Domain P13864_935-1103 6.4e-22 1 No_clan B 935 1103   
BAH Domain P13864_758-884 4.4e-21 1 No_clan B 758 884   
zf-CXXC Domain P13864_651-694 2.4e-14 1 No_clan B 650 694 DJ  L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=650-1602 C cytoplasm
A/B=650-1602 C heterochromatin
A/B=650-1602 C neuronal cell body
A/B=650-1602 C nucleoplasm
A/B=650-1602 C nucleus
A/B=650-1602 C pericentric heterochromatin
A/B=650-1602 C protein-containing complex
A/B=650-1602 C replication fork
A/B=650-1602 F chromatin binding
A/B=650-1602 F DNA (cytosine-5-)-methyltransferase activity
A/B=650-1602 F DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
A/B=650-1602 F DNA binding
A/B=650-1602 F DNA-methyltransferase activity
A/B=650-1602 F estrogen receptor binding
A/B=650-1602 F histone deacetylase binding
A/B=650-1602 F methyl-CpG binding
A/B=650-1602 F methyltransferase activity
A/B=650-1602 F promoter-specific chromatin binding
A/B=650-1602 F protein domain specific binding
A/B=650-1602 F RNA binding
A/B=650-1602 F zinc ion binding
A/B=650-1602 P cellular response to amino acid stimulus
A/B=650-1602 P cellular response to transforming growth factor beta stimulus
A/B=650-1602 P chromatin organization
A/B=650-1602 P DNA hypermethylation
A/B=650-1602 P DNA methylation
A/B=650-1602 P DNA methylation involved in embryo development
A/B=650-1602 P DNA methylation on cytosine
A/B=650-1602 P DNA methylation on cytosine within a CG sequence
A/B=650-1602 P gene silencing
A/B=650-1602 P maintenance of DNA methylation
A/B=650-1602 P negative regulation of gene expression
A/B=650-1602 P negative regulation of histone H3-K9 methylation
A/B=650-1602 P negative regulation of transcription by RNA polymerase II
A/B=650-1602 P negative regulation of transcription, DNA-templated
A/B=650-1602 P negative regulation of vascular associated smooth muscle cell apoptotic process
A/B=650-1602 P negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
A/B=650-1602 P positive regulation of DNA methylation-dependent heterochromatin assembly
A/B=650-1602 P positive regulation of gene expression
A/B=650-1602 P positive regulation of histone H3-K4 methylation
A/B=650-1602 P positive regulation of vascular associated smooth muscle cell proliferation
A/B=650-1602 P Ras protein signal transduction
A/B=650-1602 P regulation of cell population proliferation
A/B=650-1602 P regulation of gene expression
A/B=650-1602 P response to drug
A/B=650-1602 P S-adenosylmethionine metabolic process
Sequences
Download file with secondary structure created by Stride  
3pt6.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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I (dna): 
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A (protein): 
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3pt6.pdb2.pdb:   [ download sequences in FASTA format ]
D (dna): 
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J (dna): 
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B (protein): 
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