General information
PDB ID 3Q8L
Title CRYSTAL STRUCTURE OF HUMAN FLAP ENDONUCLEASE FEN1 (WT) IN COMPLEX WITH SUBSTRATE 5'-FLAP DNA, SM3+, AND K+
PDB header HYDROLASE/DNA
Date 2011-01-06
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.32
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3q8l.pdb A DEF 0
Biounits:
3q8l.pdb1.pdb A DEF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
XPG_N Family P39748_2-107 1.9e-36 1 CL0280 A 2 107 DEF  H-Bb H-Mj H-Mn S-Mj L-Bb L-Mj L-Mn 
XPG_I Family P39748_149-233 4e-29 1 CL0464 A 149 233 E  L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=2-336 C membrane
A=2-336 C mitochondrion
A=2-336 C nuclear chromosome, telomeric region
A=2-336 C nucleolus
A=2-336 C nucleoplasm
A=2-336 C nucleus
A=2-336 C protein-containing complex
A=2-336 F 5'-3' exonuclease activity
A=2-336 F 5'-flap endonuclease activity
A=2-336 F damaged DNA binding
A=2-336 F DNA binding
A=2-336 F double-stranded DNA binding
A=2-336 F double-stranded DNA exodeoxyribonuclease activity
A=2-336 F endonuclease activity
A=2-336 F exonuclease activity
A=2-336 F flap endonuclease activity
A=2-336 F magnesium ion binding
A=2-336 F manganese ion binding
A=2-336 F RNA-DNA hybrid ribonuclease activity
A=2-336 P base-excision repair
A=2-336 P DNA repair
A=2-336 P DNA replication
A=2-336 P DNA replication, removal of RNA primer
A=2-336 P double-strand break repair
A=2-336 P double-strand break repair via homologous recombination
A=2-336 P memory
A=2-336 P nucleic acid phosphodiester bond hydrolysis
A=2-336 P positive regulation of sister chromatid cohesion
A=2-336 P telomere maintenance via semi-conservative replication
A=2-336 P UV protection
Sequences
Download file with secondary structure created by Stride  
3q8l.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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E (dna): 
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F (dna): 
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A (protein): 
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