General information
PDB ID 3QSV
Title STRUCTURAL BASIS FOR DNA RECOGNITION BY CONSTITUTIVE SMAD4 MH1 DIMERS
PDB header TRANSCRIPTION/DNA
Date 2011-02-22
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.71
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3qsv.pdb ABCD EFGH 0
Biounits:
3qsv.pdb1.pdb AD EF 1
3qsv.pdb2.pdb BC GH 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MH1 Domain P97471_36-136 3e-41 1 CL0263 A 36 137 EF   
MH1 Domain P97471_36-136 3e-41 1 CL0263 B 36 137 GH  H-Bb S-Bb S-Mj L-Bb L-Mj 
MH1 Domain P97471_36-136 6e-41 1 CL0263 C 36 136 GH  S-Bb S-Mj L-Bb L-Mj 
MH1 Domain P97471_36-136 6.1e-41 1 CL0263 D 36 136 EF   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C/D=9-140 C activin responsive factor complex
A/B/C/D=9-140 C centrosome
A/B/C/D=9-140 C SMAD protein complex
A/B/C/D=9-140 C transcription factor complex
A/B/C/D=9-140 C cytoplasm
A/B/C/D=9-140 F core promoter proximal region sequence-specific DNA binding
A/B/C/D=9-140 F transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
A/B/C/D=9-140 F sequence-specific DNA binding transcription factor activity
A/B/C/D=9-140 F DNA binding
A/B/C/D=9-140 F protein binding transcription factor activity
A/B/C/D=9-140 F chromatin binding
A/B/C/D=9-140 P positive regulation of transforming growth factor beta receptor signaling pathway
A/B/C/D=9-140 P regulation of binding
A/B/C/D=9-140 P somite rostral/caudal axis specification
A/B/C/D=9-140 P palate development
A/B/C/D=9-140 P developmental growth
A/B/C/D=9-140 P regulation of transforming growth factor beta2 production
A/B/C/D=9-140 P transcription, DNA-dependent
A/B/C/D=9-140 P branching involved in ureteric bud morphogenesis
A/B/C/D=9-140 P positive regulation of pathway-restricted SMAD protein phosphorylation
A/B/C/D=9-140 P formation of anatomical boundary
A/B/C/D=9-140 P neuron fate commitment
A/B/C/D=9-140 P nephrogenic mesenchyme morphogenesis
A/B/C/D=9-140 P negative regulation of protein catabolic process
A/B/C/D=9-140 P SMAD protein signal transduction
A/B/C/D=9-140 P transforming growth factor beta receptor signaling pathway
A/B/C/D=9-140 P positive regulation of SMAD protein import into nucleus
A/B/C/D=9-140 P SMAD protein complex assembly
A/B/C/D=9-140 P positive regulation of transcription from RNA polymerase II promoter
A/B/C/D=9-140 P BMP signaling pathway
A/B/C/D=9-140 P gastrulation with mouth forming second
A/B/C/D=9-140 P sebaceous gland development
A/B/C/D=9-140 P endoderm development
A/B/C/D=9-140 P response to transforming growth factor beta stimulus
A/B/C/D=9-140 P negative regulation of cell death
A/B/C/D=9-140 P regulation of hair follicle development
A/B/C/D=9-140 P neural crest cell differentiation
A/B/C/D=9-140 P in utero embryonic development
A/B/C/D=9-140 P metanephric mesenchyme morphogenesis
A/B/C/D=9-140 P mesoderm development
A/B/C/D=9-140 P negative regulation of cell proliferation
A/B/C/D=9-140 P response to hypoxia
A/B/C/D=9-140 P negative regulation of transcription, DNA-dependent
A/B/C/D=9-140 P positive regulation of epithelial to mesenchymal transition
A/B/C/D=9-140 P cell proliferation
A/B/C/D=9-140 P negative regulation of cell growth
A/B/C/D=9-140 P positive regulation of BMP signaling pathway
Sequences
Download file with secondary structure created by Stride  
3qsv.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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D (protein): 
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3qsv.pdb2.pdb:   [ download sequences in FASTA format ]
G (dna): 
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H (dna): 
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B (protein): 
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C (protein): 
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