General information
PDB ID 3THX
Title HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 3 BASES (LOOP3) AND ADP
PDB header DNA BINDING PROTEIN/DNA
Date 2011-08-19
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.7
Kind dna
Organism HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3thx.pdb AB DE 0
Biounits:
3thx.pdb1.pdb AB DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MutS_V Domain P43246_665-852 3e-78 1 CL0023 A 665 852   
MutS_III Domain P43246_305-609 7.7e-36 1 No_clan A 305 609 E  L-Bb 
MutS_II Domain P43246_145-290 4.8e-22 1 No_clan A 146 290   
MutS_I Domain P43246_17-132 6.1e-20 1 No_clan A 17 132 E   
MutS_IV Domain P43246_473-569 1.7e-13 1 No_clan A 473 569 E  L-Bb 
MutS_V Domain P20585_892-1094 4.9e-63 1 CL0023 B 883 1085   
MutS_III Domain P20585_540-838 1.5e-38 1 No_clan B 531 829 E  S-Bb L-Bb 
MutS_I Domain P20585_230-343 2.1e-32 1 No_clan B 221 334 DE  H-Bb S-Bb L-Bb L-Mj L-Mn 
MutS_II Domain P20585_366-523 9.1e-31 1 No_clan B 357 514   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=1-934 C membrane
A=1-934 C mismatch repair complex
A=1-934 C MutSalpha complex
A=1-934 C MutSbeta complex
A=1-934 C nuclear chromosome, telomeric region
A=1-934 C nucleoplasm
A=1-934 C nucleus
A=1-934 F ATP binding
A=1-934 F centromeric DNA binding
A=1-934 F chromatin binding
A=1-934 F damaged DNA binding
A=1-934 F DNA binding
A=1-934 F DNA-dependent ATPase activity
A=1-934 F double-strand/single-strand DNA junction binding
A=1-934 F enzyme binding
A=1-934 F guanine/thymine mispair binding
A=1-934 F protein C-terminus binding
A=1-934 F protein homodimerization activity
A=1-934 F protein kinase binding
A=1-934 P B cell differentiation
A=1-934 P B cell mediated immunity
A=1-934 P cell cycle arrest
A=1-934 P determination of adult lifespan
A=1-934 P DNA recombination
A=1-934 P DNA repair
A=1-934 P double-strand break repair
A=1-934 P germ cell development
A=1-934 P in utero embryonic development
A=1-934 P intra-S DNA damage checkpoint
A=1-934 P intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
A=1-934 P isotype switching
A=1-934 P maintenance of DNA repeat elements
A=1-934 P male gonad development
A=1-934 P mismatch repair
A=1-934 P negative regulation of DNA recombination
A=1-934 P negative regulation of neuron apoptotic process
A=1-934 P oxidative phosphorylation
A=1-934 P positive regulation of helicase activity
A=1-934 P positive regulation of isotype switching to IgA isotypes
A=1-934 P positive regulation of isotype switching to IgG isotypes
A=1-934 P postreplication repair
A=1-934 P protein localization to chromatin
A=1-934 P response to UV-B
A=1-934 P response to X-ray
A=1-934 P somatic hypermutation of immunoglobulin genes
A=1-934 P somatic recombination of immunoglobulin gene segments
A=1-934 P somatic recombination of immunoglobulin genes involved in immune response
B=219-1134 C membrane
B=219-1134 C mismatch repair complex
B=219-1134 C MutSbeta complex
B=219-1134 C nucleoplasm
B=219-1134 C nucleus
B=219-1134 F ATP binding
B=219-1134 F DNA insertion or deletion binding
B=219-1134 F DNA-dependent ATPase activity
B=219-1134 F enzyme binding
B=219-1134 P DNA repair
B=219-1134 P maintenance of DNA repeat elements
B=219-1134 P meiotic mismatch repair
B=219-1134 P mismatch repair
B=219-1134 P mitotic recombination
B=219-1134 P negative regulation of DNA recombination
B=219-1134 P positive regulation of helicase activity
B=219-1134 P reciprocal meiotic recombination
B=219-1134 P removal of nonhomologous ends
B=219-1134 P replication fork arrest
B=219-1134 P somatic recombination of immunoglobulin gene segments
Sequences
Download file with secondary structure created by Stride  
3thx.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
Click "SHOW" for view sequence
E (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text