General information
PDB ID 3V6D
Title CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) CROSS-LINKED WITH AZT-TERMINATED DNA
PDB header TRANSFERASE/DNA
Date 2011-12-19
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.7
Kind dna
Organism HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3v6d.pdb ABCD TPEF 0
Biounits:
3v6d.pdb1.pdb AB TP 1
3v6d.pdb2.pdb CD EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P03366_917-1018 2.2e-59 1 No_clan A 318 419 P  S-Bb L-Bb 
RNase_H Domain P03366_1035-1153 7.5e-27 1 CL0219 A 436 554 PT  H-Bb L-Bb 
RVT_thumb Domain P03366_840-903 3.6e-18 1 No_clan A 241 304 P   
RVT_connect Domain P03366_917-1018 1.3e-59 1 No_clan B 318 419   
RVT_thumb Domain P03366_840-903 3.8e-20 1 No_clan B 241 304   
RVT_connect Domain P03366_917-1018 2.2e-59 1 No_clan C 318 419 EF  S-Bb L-Bb 
RNase_H Domain P03366_1035-1153 7.5e-27 1 CL0219 C 436 554 F  H-Bb L-Bb 
RVT_thumb Domain P03366_840-903 3.6e-18 1 No_clan C 241 304 EF  L-Bb 
RVT_connect Domain P03366_917-1018 1.3e-59 1 No_clan D 318 419 F  H-Bb 
RVT_thumb Domain P03366_840-903 3.8e-20 1 No_clan D 241 304   
RVT_1 Family P03366_662-833 1.4e-34 1 CL0027 A 63 234 PT   
RVT_1 Family P03366_662-833 6.1e-33 1 CL0027 B 63 253   
RVT_1 Family P03366_662-833 1.4e-34 1 CL0027 C 63 234 FE   
RVT_1 Family P03366_662-833 6.1e-33 1 CL0027 D 63 253   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/C=600-1153, B/D=600-1027 C cytosol
A/C=600-1153, B/D=600-1027 C host cell plasma membrane
A/C=600-1153, B/D=600-1027 C host cell cytoplasm
A/C=600-1153, B/D=600-1027 C nucleoplasm
A/C=600-1153, B/D=600-1027 C host cell nucleus
A/C=600-1153, B/D=600-1027 C viral capsid
A/C=600-1153, B/D=600-1027 C membrane
A/C=600-1153, B/D=600-1027 F ribonuclease H activity
A/C=600-1153, B/D=600-1027 F exoribonuclease H activity
A/C=600-1153, B/D=600-1027 F DNA binding
A/C=600-1153, B/D=600-1027 F RNA binding
A/C=600-1153, B/D=600-1027 F structural molecule activity
A/C=600-1153, B/D=600-1027 F RNA-directed DNA polymerase activity
A/C=600-1153, B/D=600-1027 F DNA-directed DNA polymerase activity
A/C=600-1153, B/D=600-1027 F aspartic-type endopeptidase activity
A/C=600-1153, B/D=600-1027 F zinc ion binding
A/C=600-1153, B/D=600-1027 P entry into host cell
A/C=600-1153, B/D=600-1027 P viral procapsid maturation
A/C=600-1153, B/D=600-1027 P RNA-dependent DNA replication
A/C=600-1153, B/D=600-1027 P nucleic acid phosphodiester bond hydrolysis
A/C=600-1153, B/D=600-1027 P uncoating of virus
A/C=600-1153, B/D=600-1027 P modulation by virus of host apoptosis
A/C=600-1153, B/D=600-1027 P provirus integration
A/C=600-1153, B/D=600-1027 P proteolysis
Sequences
Download file with secondary structure created by Stride  
3v6d.pdb1.pdb:   [ download sequences in FASTA format ]
P (dna): 
Click "SHOW" for view sequence
T (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
3v6d.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
Click "SHOW" for view sequence
F (dna): 
Click "SHOW" for view sequence
C (protein): 
Click "SHOW" for view sequence
D (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2019

text