General information
PDB ID 3VD0
Title STRUCTURE OF P73 DNA BINDING DOMAIN TETRAMER MODULATES P73 TRANSACTIVATION
PDB header ANTITUMOR PROTEIN/DNA
Date 2012-01-04
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.95
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3vd0.pdb ABCDIJKL EFGHMNOP 0
Biounits:
3vd0.pdb1.pdb ABCD EFGH 1
3vd0.pdb2.pdb IJKL MNOP 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
P53 Domain O15350_117-309 3.5e-64 1 CL0073 A 117 309 EF  H-Mj L-Bb L-Mj 
P53 Domain O15350_117-309 3.4e-64 1 CL0073 B 117 309 EF  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.5e-64 1 CL0073 C 117 309 GH  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.4e-64 1 CL0073 D 117 309 GH  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.3e-64 1 CL0073 I 117 309 MN  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.3e-64 1 CL0073 J 117 309 MN  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.8e-64 1 CL0073 K 117 309 OP  H-Mj S-Bb L-Bb L-Mj 
P53 Domain O15350_117-309 3.4e-64 1 CL0073 L 117 309 OP  H-Mj S-Bb L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C/D/I/J/K/L=115-312 C cell junction
A/B/C/D/I/J/K/L=115-312 C cytosol
A/B/C/D/I/J/K/L=115-312 C Golgi apparatus
A/B/C/D/I/J/K/L=115-312 C intracellular membrane-bounded organelle
A/B/C/D/I/J/K/L=115-312 C mitochondrion
A/B/C/D/I/J/K/L=115-312 C nuclear chromatin
A/B/C/D/I/J/K/L=115-312 C nucleoplasm
A/B/C/D/I/J/K/L=115-312 C nucleus
A/B/C/D/I/J/K/L=115-312 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B/C/D/I/J/K/L=115-312 F DNA-binding transcription factor activity
A/B/C/D/I/J/K/L=115-312 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B/C/D/I/J/K/L=115-312 F identical protein binding
A/B/C/D/I/J/K/L=115-312 F MDM2/MDM4 family protein binding
A/B/C/D/I/J/K/L=115-312 F metal ion binding
A/B/C/D/I/J/K/L=115-312 F p53 binding
A/B/C/D/I/J/K/L=115-312 F protein kinase binding
A/B/C/D/I/J/K/L=115-312 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B/C/D/I/J/K/L=115-312 F transcription factor binding
A/B/C/D/I/J/K/L=115-312 F transcription regulatory region sequence-specific DNA binding
A/B/C/D/I/J/K/L=115-312 P activation of MAPK activity
A/B/C/D/I/J/K/L=115-312 P cell cycle arrest
A/B/C/D/I/J/K/L=115-312 P cellular response to DNA damage stimulus
A/B/C/D/I/J/K/L=115-312 P intrinsic apoptotic signaling pathway in response to DNA damage
A/B/C/D/I/J/K/L=115-312 P intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
A/B/C/D/I/J/K/L=115-312 P kidney development
A/B/C/D/I/J/K/L=115-312 P mismatch repair
A/B/C/D/I/J/K/L=115-312 P negative regulation of cardiac muscle cell proliferation
A/B/C/D/I/J/K/L=115-312 P negative regulation of cell population proliferation
A/B/C/D/I/J/K/L=115-312 P negative regulation of neuron differentiation
A/B/C/D/I/J/K/L=115-312 P positive regulation of cell cycle arrest
A/B/C/D/I/J/K/L=115-312 P positive regulation of oligodendrocyte differentiation
A/B/C/D/I/J/K/L=115-312 P positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
A/B/C/D/I/J/K/L=115-312 P positive regulation of transcription by RNA polymerase II
A/B/C/D/I/J/K/L=115-312 P positive regulation of transcription, DNA-templated
A/B/C/D/I/J/K/L=115-312 P protein tetramerization
A/B/C/D/I/J/K/L=115-312 P regulation of apoptotic process
A/B/C/D/I/J/K/L=115-312 P regulation of gene expression
A/B/C/D/I/J/K/L=115-312 P regulation of hematopoietic stem cell differentiation
A/B/C/D/I/J/K/L=115-312 P regulation of mitotic cell cycle
A/B/C/D/I/J/K/L=115-312 P regulation of signal transduction by p53 class mediator
A/B/C/D/I/J/K/L=115-312 P response to drug
A/B/C/D/I/J/K/L=115-312 P response to organonitrogen compound
A/B/C/D/I/J/K/L=115-312 P viral process
Sequences
Download file with secondary structure created by Stride  
3vd0.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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G (dna): 
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H (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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3vd0.pdb2.pdb:   [ download sequences in FASTA format ]
M (dna): 
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N (dna): 
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O (dna): 
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P (dna): 
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I (protein): 
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J (protein): 
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K (protein): 
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L (protein): 
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