General information
PDB ID 4CGZ
Title CRYSTAL STRUCTURE OF THE BLOOM'S SYNDROME HELICASE BLM IN COMPLEX WITH DNA
PDB header HYDROLASE/DNA
Date 2013-11-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.2
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4cgz.pdb A BC 0
Biounits:
4cgz.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DEAD Domain P54132_669-841 6.1e-20 1 CL0023 A 669 841   
RQC Domain P54132_1071-1193 1.8e-18 1 CL0123 A 1071 1211 BC  S-Bb L-Bb L-Mn 
RecQ_Zn_bind Domain P54132_995-1067 3.5e-17 1 No_clan A 995 1067 C   
Helicase_C Domain P54132_874-984 8.1e-15 1 CL0023 A 873 984 C   
HRDC Domain P54132_1215-1282 2.8e-12 1 CL0426 A 1215 1282   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=636-1298 C chromosome
A=636-1298 C cytoplasm
A=636-1298 C cytosol
A=636-1298 C lateral element
A=636-1298 C nuclear chromosome
A=636-1298 C nuclear matrix
A=636-1298 C nucleolus
A=636-1298 C nucleoplasm
A=636-1298 C nucleus
A=636-1298 C PML body
A=636-1298 C protein-containing complex
A=636-1298 C replication fork
A=636-1298 F 3'-5' DNA helicase activity
A=636-1298 F 8-hydroxy-2'-deoxyguanosine DNA binding
A=636-1298 F annealing helicase activity
A=636-1298 F ATP binding
A=636-1298 F ATPase activity
A=636-1298 F bubble DNA binding
A=636-1298 F DNA binding
A=636-1298 F DNA helicase activity
A=636-1298 F DNA-dependent ATPase activity
A=636-1298 F forked DNA-dependent helicase activity
A=636-1298 F four-way junction DNA binding
A=636-1298 F four-way junction helicase activity
A=636-1298 F G-quadruplex DNA binding
A=636-1298 F helicase activity
A=636-1298 F identical protein binding
A=636-1298 F p53 binding
A=636-1298 F protein homodimerization activity
A=636-1298 F single-stranded DNA binding
A=636-1298 F telomeric D-loop binding
A=636-1298 F telomeric G-quadruplex DNA binding
A=636-1298 F Y-form DNA binding
A=636-1298 F zinc ion binding
A=636-1298 P cellular response to camptothecin
A=636-1298 P cellular response to DNA damage stimulus
A=636-1298 P cellular response to hydroxyurea
A=636-1298 P cellular response to ionizing radiation
A=636-1298 P DNA double-strand break processing
A=636-1298 P DNA duplex unwinding
A=636-1298 P DNA recombination
A=636-1298 P DNA repair
A=636-1298 P DNA replication
A=636-1298 P DNA unwinding involved in DNA replication
A=636-1298 P double-strand break repair via homologous recombination
A=636-1298 P G-quadruplex DNA unwinding
A=636-1298 P mitotic G2 DNA damage checkpoint
A=636-1298 P negative regulation of cell division
A=636-1298 P negative regulation of DNA recombination
A=636-1298 P positive regulation of transcription, DNA-templated
A=636-1298 P protein complex oligomerization
A=636-1298 P protein homooligomerization
A=636-1298 P regulation of cyclin-dependent protein serine/threonine kinase activity
A=636-1298 P regulation of DNA-dependent DNA replication
A=636-1298 P regulation of signal transduction by p53 class mediator
A=636-1298 P replication fork processing
A=636-1298 P replication fork protection
A=636-1298 P response to X-ray
A=636-1298 P t-circle formation
A=636-1298 P telomere maintenance
A=636-1298 P telomeric D-loop disassembly
Sequences
Download file with secondary structure created by Stride  
4cgz.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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