General information
PDB ID 4DA4
Title STRUCTURE OF MOUSE DNMT1 (731-1602) BOUND TO HEMIMETHYLATED CPG DNA
PDB header TRANSFERASE/DNA
Date 2012-01-12
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism MUS MUSCULUS
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4da4.pdb AB CDEF 0
Biounits:
4da4.pdb1.pdb A CD 1
4da4.pdb2.pdb B EF 1
Pfam domains
Name: Type: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Action:
DNA_methylase Domain 1.2e-47 1 CL0063 A 1142 1596 CD
BAH Domain 4.8e-22 1 No_clan A 935 1103 D
BAH Domain 3.5e-21 1 No_clan A 758 884
DNA_methylase Domain 1.2e-47 1 CL0063 B 1142 1596 EF
BAH Domain 4.7e-22 1 No_clan B 935 1103 F
BAH Domain 1.7e-20 1 No_clan B 758 884
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=731-1602 C nucleus
A/B=731-1602 C replication fork
A/B=731-1602 C centromeric heterochromatin
A/B=731-1602 C cytoplasm
A/B=731-1602 F DNA (cytosine-5-)-methyltransferase activity
A/B=731-1602 F methyl-CpG binding
A/B=731-1602 F RNA binding
A/B=731-1602 F zinc ion binding
A/B=731-1602 P positive regulation of histone H3-K4 methylation
A/B=731-1602 P gene silencing
A/B=731-1602 P regulation of cell proliferation
A/B=731-1602 P chromatin modification
A/B=731-1602 P negative regulation of histone H3-K9 methylation
A/B=731-1602 P positive regulation of gene expression
A/B=731-1602 P transcription, DNA-dependent
A/B=731-1602 P negative regulation of transcription, DNA-dependent
A/B=731-1602 P maintenance of DNA methylation
A/B=731-1602 P cellular response to amino acid stimulus
Sequences
Download file with secondary structure created by Stride  
4da4.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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4da4.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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B (protein): 
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