General information
PDB ID 4NW3
Title CRYSTAL STRUCTURE OF MLL CXXC DOMAIN IN COMPLEX WITH A CPG DNA
PDB header DNA BINDING PROTEIN/DNA
Date 2013-12-05
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.82
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4nw3.pdb A BC 0
Biounits:
4nw3.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-CXXC Domain Q03164_1147-1194 9.3e-16 1 No_clan A 1150 1194 BC  S-Bb L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=1147-1204 C cytosol
A=1147-1204 C histone methyltransferase complex
A=1147-1204 C MLL1 complex
A=1147-1204 C nucleoplasm
A=1147-1204 C nucleus
A=1147-1204 F AT DNA binding
A=1147-1204 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=1147-1204 F histone methyltransferase activity (H3-K4 specific)
A=1147-1204 F identical protein binding
A=1147-1204 F lysine-acetylated histone binding
A=1147-1204 F protein homodimerization activity
A=1147-1204 F transcription regulatory region sequence-specific DNA binding
A=1147-1204 F unmethylated CpG binding
A=1147-1204 F zinc ion binding
A=1147-1204 P apoptotic process
A=1147-1204 P circadian regulation of gene expression
A=1147-1204 P embryonic hemopoiesis
A=1147-1204 P histone H3-K4 dimethylation
A=1147-1204 P histone H3-K4 methylation
A=1147-1204 P histone H3-K4 monomethylation
A=1147-1204 P histone H3-K4 trimethylation
A=1147-1204 P histone H4-K16 acetylation
A=1147-1204 P negative regulation of DNA methylation
A=1147-1204 P positive regulation of cellular response to drug
A=1147-1204 P positive regulation of histone H3-K4 methylation
A=1147-1204 P positive regulation of transcription by RNA polymerase II
A=1147-1204 P positive regulation of transcription, DNA-templated
A=1147-1204 P positive regulation of transporter activity
A=1147-1204 P protein-containing complex assembly
A=1147-1204 P regulation of hematopoietic stem cell differentiation
A=1147-1204 P regulation of histone H3-K14 acetylation
A=1147-1204 P regulation of histone H3-K9 acetylation
A=1147-1204 P regulation of megakaryocyte differentiation
Sequences
Download file with secondary structure created by Stride  
4nw3.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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