General information
PDB ID 4ROE
Title HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO RPPH1 PROMOTER
PDB header TRANSCRIPTION
Date 2014-10-28
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.2
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4roe.pdb AB NT 0
Biounits:
4roe.pdb1.pdb AB NT 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
TFIIB Domain Q9HAW0_63-157 2.9e-05 1 CL0065 A 65 159 NT  H-Bb L-Bb L-Mn 
TBP Domain P20226_162-244 6e-33 1 CL0407 B 162 244 NT  S-Bb S-Mn L-Bb L-Mn 
TBP Domain P20226_252-335 1.5e-31 1 CL0407 B 252 334 NT  S-Bb S-Mn L-Bb L-Mn 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=62-419 C nucleoplasm
A=62-419 C nucleus
A=62-419 C transcription factor TFIIIB complex
A=62-419 C transcription preinitiation complex
A=62-419 F metal ion binding
A=62-419 F RNA polymerase II complex recruiting activity
A=62-419 F RNA polymerase II core promoter sequence-specific DNA binding
A=62-419 F RNA polymerase III type 3 promoter sequence-specific DNA binding
A=62-419 F TBP-class protein binding
A=62-419 F transcription factor binding
A=62-419 P cellular response to oxidative stress
A=62-419 P DNA-templated transcription, initiation
A=62-419 P regulation of transcription by RNA polymerase III
A=62-419 P RNA polymerase II preinitiation complex assembly
A=62-419 P transcriptional start site selection at RNA polymerase II promoter
B=159-339 C cytoplasm
B=159-339 C female pronucleus
B=159-339 C male pronucleus
B=159-339 C nuclear chromatin
B=159-339 C nuclear euchromatin
B=159-339 C nucleoplasm
B=159-339 C nucleus
B=159-339 C protein-containing complex
B=159-339 C transcription factor TFIIA complex
B=159-339 C transcription factor TFIID complex
B=159-339 C transcription factor TFIIIB complex
B=159-339 C transcription preinitiation complex
B=159-339 C transcription regulator complex
B=159-339 F aryl hydrocarbon receptor binding
B=159-339 F core promoter sequence-specific DNA binding
B=159-339 F DNA-binding transcription factor activity
B=159-339 F enzyme binding
B=159-339 F repressing transcription factor binding
B=159-339 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
B=159-339 F RNA polymerase II core promoter sequence-specific DNA binding
B=159-339 F RNA polymerase II general transcription initiation factor activity
B=159-339 F RNA polymerase II general transcription initiation factor binding
B=159-339 F RNA polymerase II repressing transcription factor binding
B=159-339 F RNA polymerase III general transcription initiation factor activity
B=159-339 F RNA polymerase III transcription regulatory region sequence-specific DNA binding
B=159-339 F TFIIB-class transcription factor binding
B=159-339 F transcription factor binding
B=159-339 F transcription regulatory region sequence-specific DNA binding
B=159-339 P positive regulation of gene expression, epigenetic
B=159-339 P positive regulation of transcription, DNA-templated
B=159-339 P regulation of signal transduction by p53 class mediator
B=159-339 P RNA polymerase II preinitiation complex assembly
B=159-339 P RNA polymerase III preinitiation complex assembly
B=159-339 P snRNA transcription by RNA polymerase II
B=159-339 P spermatogenesis
B=159-339 P termination of RNA polymerase I transcription
B=159-339 P transcription by RNA polymerase II
B=159-339 P transcription by RNA polymerase III
B=159-339 P transcription elongation from RNA polymerase I promoter
B=159-339 P transcription initiation from RNA polymerase I promoter
B=159-339 P transcription initiation from RNA polymerase II promoter
B=159-339 P viral process
Sequences
Download file with secondary structure created by Stride  
4roe.pdb1.pdb:   [ download sequences in FASTA format ]
N (dna): 
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T (dna): 
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A (protein): 
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B (protein): 
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