General information
PDB ID 4XLS
Title CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX WITH CARD CONTAINING UPSTREAM FORK PROMOTER.
PDB header TRANSCRIPTION
Date 2015-01-13
Experimental method X-RAY DIFFRACTION
Resolution (A) 4.01
Kind dna
Organism THERMUS AQUATICUS, THERMUS THERMOPHILUS JL-18, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4xls.pdb ABCDEFGHIJKLMN OPRS 0
Biounits:
4xls.pdb1.pdb ABCDEFM OP 1
4xls.pdb2.pdb GHIJKLN RS 1
4xls.pdb3.pdb ABCDEF OP 1
4xls.pdb4.pdb GHIJKL RS 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan A 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan A 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan A 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan A 52 180   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 A 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 A 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 A 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 A 26 222   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan B 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan B 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan B 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan B 52 180   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 B 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 B 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 B 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 B 26 222   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 C 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 C 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 C 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 C 596 1026   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan C 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan C 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan C 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan C 393 461   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan C 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan C 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan C 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan C 1028 1104   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan C 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan C 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan C 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan C 471 535   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan C 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan C 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan C 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan C 142 334   
RNA_pol_Rpb1_1 Domain Q9KWU6_423-618 3.2e-46 1 No_clan D 423 618   
RNA_pol_Rpb1_1 Domain Q9KWU6_423-618 3.2e-46 1 No_clan D 423 618   
RNA_pol_Rpb1_1 Domain Q9KWU6_423-618 3.2e-46 1 No_clan D 423 618   
RNA_pol_Rpb1_1 Domain Q9KWU6_423-618 3.2e-46 1 No_clan D 423 618   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.4e-35 1 No_clan D 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.4e-35 1 No_clan D 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.4e-35 1 No_clan D 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.4e-35 1 No_clan D 620 765   
RNA_pol_Rpb1_1 Domain Q9KWU6_2-192 1.6e-33 1 No_clan D 2 192 O  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-192 1.6e-33 1 No_clan D 2 192 O  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-192 1.6e-33 1 No_clan D 2 192 O  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-192 1.6e-33 1 No_clan D 2 192 O  L-Bb 
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.6e-32 1 No_clan D 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.6e-32 1 No_clan D 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.6e-32 1 No_clan D 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.6e-32 1 No_clan D 1064 1254   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 7.8e-30 1 No_clan D 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 7.8e-30 1 No_clan D 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 7.8e-30 1 No_clan D 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 7.8e-30 1 No_clan D 768 954   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5.6e-15 1 No_clan D 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5.6e-15 1 No_clan D 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5.6e-15 1 No_clan D 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5.6e-15 1 No_clan D 983 1069   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 3e-13 1 No_clan D 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 3e-13 1 No_clan D 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 3e-13 1 No_clan D 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 3e-13 1 No_clan D 1261 1432   
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 F 202 272 O  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 F 202 272 O  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 F 202 272 O  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 F 202 272 O  H-Bb H-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 F 372 425 PO  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 F 372 425 PO  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 F 372 425 PO  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 F 372 425 PO  H-Bb H-Mj L-Bb L-Mj 
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan G 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan G 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan G 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan G 52 180   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 G 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 G 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 G 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 G 26 222   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan H 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan H 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan H 52 180   
RNA_pol_A_bac Domain Q9KWU8_52-179 4.3e-26 1 No_clan H 52 180   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 H 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 H 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 H 26 222   
RNA_pol_L Domain Q9KWU8_26-222 1.9e-21 1 CL0509 H 26 222   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 I 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 I 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 I 596 1026   
RNA_pol_Rpb2_6 Domain Q9KWU7_596-1026 8e-148 1 CL0410 I 596 1026   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan I 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan I 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan I 393 461   
RNA_pol_Rpb2_3 Domain Q9KWU7_393-461 5.1e-28 1 No_clan I 393 461   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan I 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan I 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan I 1028 1104   
RNA_pol_Rpb2_7 Domain Q9KWU7_1028-1104 3.2e-26 1 No_clan I 1028 1104   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan I 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan I 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan I 471 535   
RNA_pol_Rpb2_45 Domain Q9KWU7_471-535 8.4e-24 1 No_clan I 471 535   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan I 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan I 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan I 142 334   
RNA_pol_Rpb2_2 Domain Q9KWU7_142-334 4.9e-11 1 No_clan I 142 334   
RNA_pol_Rpb1_1 Domain Q9KWU6_2-495 3.4e-82 1 No_clan J 2 618 R  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-495 3.4e-82 1 No_clan J 2 618 R  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-495 3.4e-82 1 No_clan J 2 618 R  L-Bb 
RNA_pol_Rpb1_1 Domain Q9KWU6_2-495 3.4e-82 1 No_clan J 2 618 R  L-Bb 
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.3e-35 1 No_clan J 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.3e-35 1 No_clan J 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.3e-35 1 No_clan J 620 765   
RNA_pol_Rpb1_2 Domain Q9KWU6_620-765 1.3e-35 1 No_clan J 620 765   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.4e-32 1 No_clan J 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.4e-32 1 No_clan J 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.4e-32 1 No_clan J 1064 1254   
RNA_pol_Rpb1_5 Domain Q9KWU6_1064-1291 1.4e-32 1 No_clan J 1064 1254   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 6.9e-30 1 No_clan J 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 6.9e-30 1 No_clan J 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 6.9e-30 1 No_clan J 768 954   
RNA_pol_Rpb1_3 Domain Q9KWU6_768-954 6.9e-30 1 No_clan J 768 954   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5e-15 1 No_clan J 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5e-15 1 No_clan J 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5e-15 1 No_clan J 983 1069   
RNA_pol_Rpb1_4 Domain Q9KWU6_983-1069 5e-15 1 No_clan J 983 1069   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 2.7e-13 1 No_clan J 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 2.7e-13 1 No_clan J 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 2.7e-13 1 No_clan J 1261 1432   
RNA_pol_Rpb1_5 Domain Q9KWU6_1269-1432 2.7e-13 1 No_clan J 1261 1432   
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 L 202 272 R  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 L 202 272 R  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 L 202 272 R  H-Bb H-Mj 
Sigma70_r2 Domain Q9EZJ8_202-272 2.6e-20 1 CL0123 L 202 272 R  H-Bb H-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 L 372 425 RS  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 L 372 425 RS  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 L 372 425 RS  H-Bb H-Mj L-Bb L-Mj 
Sigma70_r4 Domain Q9EZJ8_372-425 2.7e-18 1 CL0123 L 372 425 RS  H-Bb H-Mj L-Bb L-Mj 
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan C 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan C 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan C 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan C 17 380   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan E 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan E 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan E 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan E 8 75   
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 F 281 360 P  H-Mj 
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 F 281 360 P  H-Mj 
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 F 281 360 P  H-Mj 
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 F 281 360 P  H-Mj 
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan F 95 127 O   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan F 95 127 O   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan F 95 127 O   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan F 95 127 O   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan I 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan I 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan I 17 380   
RNA_pol_Rpb2_1 Family Q9KWU7_17-380 3.3e-40 1 No_clan I 17 380   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan K 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan K 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan K 8 75   
RNA_pol_Rpb6 Family Q9EVV4_8-75 1.5e-07 1 No_clan K 8 75   
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 L 281 360   
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 L 281 360   
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 L 281 360   
Sigma70_r3 Family Q9EZJ8_281-360 1.7e-26 1 CL0123 L 281 360   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan L 95 127 R   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan L 95 127 R   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan L 95 127 R   
Sigma70_r1_2 Family Q9EZJ8_94-127 1.3e-14 1 No_clan L 95 127 R   
CarD_CdnL_TRCF Family H9ZP94_4-112 3.8e-13 1 CL0123 M 4 112 O   
CarD_CdnL_TRCF Family H9ZP94_4-112 3.8e-13 1 CL0123 N 4 112 R   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/G/H=1-314 F DNA binding
A/B/G/H=1-314 F DNA-directed 5'-3' RNA polymerase activity
A/B/G/H=1-314 F protein dimerization activity
A/B/G/H=1-314 P transcription, DNA-templated
C/I=1-1119 F DNA binding
C/I=1-1119 F DNA-directed 5'-3' RNA polymerase activity
C/I=1-1119 F ribonucleoside binding
C/I=1-1119 P transcription, DNA-templated
D/J=1-1524 F DNA binding
D/J=1-1524 F DNA-directed 5'-3' RNA polymerase activity
D/J=1-1524 F magnesium ion binding
D/J=1-1524 F zinc ion binding
D/J=1-1524 P transcription, DNA-templated
E/K=1-99 F DNA binding
E/K=1-99 F DNA-directed 5'-3' RNA polymerase activity
E/K=1-99 P transcription, DNA-templated
F/L=92-438 C cytoplasm
F/L=92-438 F DNA binding
F/L=92-438 F DNA-binding transcription factor activity
F/L=92-438 F sigma factor activity
F/L=92-438 P transcription initiation from bacterial-type RNA polymerase promoter
Sequences
Download file with secondary structure created by Stride  
4xls.pdb1.pdb:   [ download sequences in FASTA format ]
O (dna): 
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P (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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M (protein): 
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4xls.pdb2.pdb:   [ download sequences in FASTA format ]
R (dna): 
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S (dna): 
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G (protein): 
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H (protein): 
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I (protein): 
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J (protein): 
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K (protein): 
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L (protein): 
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N (protein): 
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4xls.pdb3.pdb:   [ download sequences in FASTA format ]
O (dna): 
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P (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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4xls.pdb4.pdb:   [ download sequences in FASTA format ]
R (dna): 
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S (dna): 
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G (protein): 
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H (protein): 
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I (protein): 
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J (protein): 
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K (protein): 
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L (protein): 
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