General information
PDB ID 5BT2
Title MECP2 MBD DOMAIN (A140V) IN COMPLEX WITH METHYLATED DNA
PDB header DNA BINDING PROTEIN/DNA
Date 2015-06-02
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5bt2.pdb A BC 0
Biounits:
5bt2.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MBD Domain P51608_91-162 6.2e-18 1 CL0081 A 93 161 BC  H-Bb S-Bb S-Mj L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=77-167 C centrosome
A=77-167 C cytosol
A=77-167 C extracellular space
A=77-167 C heterochromatin
A=77-167 C host cell nucleus
A=77-167 C mitochondrion
A=77-167 C nucleoplasm
A=77-167 C nucleus
A=77-167 C postsynapse
A=77-167 F chromatin binding
A=77-167 F DNA binding
A=77-167 F DNA-binding transcription factor activity
A=77-167 F double-stranded methylated DNA binding
A=77-167 F methyl-CpG binding
A=77-167 F mRNA binding
A=77-167 F protein domain specific binding
A=77-167 F protein N-terminus binding
A=77-167 F RNA binding
A=77-167 F siRNA binding
A=77-167 F transcription corepressor activity
A=77-167 F transcription factor binding
A=77-167 P adult locomotory behavior
A=77-167 P behavioral fear response
A=77-167 P cardiolipin metabolic process
A=77-167 P catecholamine secretion
A=77-167 P cellular biogenic amine metabolic process
A=77-167 P cerebellum development
A=77-167 P chromatin silencing
A=77-167 P dendrite development
A=77-167 P excitatory postsynaptic potential
A=77-167 P glucocorticoid metabolic process
A=77-167 P glutamine metabolic process
A=77-167 P histone acetylation
A=77-167 P histone methylation
A=77-167 P inositol metabolic process
A=77-167 P long-term memory
A=77-167 P long-term synaptic potentiation
A=77-167 P mitochondrial electron transport, ubiquinol to cytochrome c
A=77-167 P mitotic spindle organization
A=77-167 P negative regulation of angiogenesis
A=77-167 P negative regulation of blood vessel endothelial cell migration
A=77-167 P negative regulation of gene expression
A=77-167 P negative regulation of neuron apoptotic process
A=77-167 P negative regulation of smooth muscle cell differentiation
A=77-167 P negative regulation of transcription by RNA polymerase II
A=77-167 P negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
A=77-167 P negative regulation of transcription, DNA-templated
A=77-167 P nervous system process involved in regulation of systemic arterial blood pressure
A=77-167 P neuron maturation
A=77-167 P pathogenesis
A=77-167 P phosphatidylcholine metabolic process
A=77-167 P positive regulation of cell population proliferation
A=77-167 P positive regulation of DNA methylation
A=77-167 P positive regulation of G2/M transition of mitotic cell cycle
A=77-167 P positive regulation of histone H3-K9 trimethylation
A=77-167 P positive regulation of microtubule nucleation
A=77-167 P positive regulation of transcription, DNA-templated
A=77-167 P post-embryonic development
A=77-167 P proprioception
A=77-167 P protein localization
A=77-167 P regulation of gene expression by genetic imprinting
A=77-167 P regulation of respiratory gaseous exchange by nervous system process
A=77-167 P respiratory gaseous exchange by respiratory system
A=77-167 P response to hypoxia
A=77-167 P sensory perception of pain
A=77-167 P social behavior
A=77-167 P startle response
A=77-167 P synapse assembly
A=77-167 P transcription initiation from RNA polymerase II promoter
A=77-167 P ventricular system development
A=77-167 P visual learning
Sequences
Download file with secondary structure created by Stride  
5bt2.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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