General information
PDB ID 5EH2
Title HUMAN PRDM9 ALLELE-A ZNF DOMAIN WITH ASSOCIATED RECOMBINATION HOTSPOT DNA SEQUENCE III
PDB header TRANSCRIPTION/DNA
Date 2015-10-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.05
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5eh2.pdb EF CDAB 0
Biounits:
5eh2.pdb1.pdb F CD 1
5eh2.pdb2.pdb E AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-H2C2_2 Domain Q9NQV7_791-816 4.4e-08 0 CL0361 E 789 814 AB  H-Bb H-Mj S-Bb L-Bb L-Mj 
zf-H2C2_2 Domain Q9NQV7_735-759 1e-07 0 CL0361 E 733 757 A  H-Bb H-Mj H-Mn 
zf-H2C2_2 Domain Q9NQV7_763-787 1e-07 0 CL0361 E 761 785 AB  H-Bb H-Mj L-Bb L-Mj 
zf-H2C2_2 Domain Q9NQV7_791-816 4.3e-08 0 CL0361 F 789 814 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
zf-H2C2_2 Domain Q9NQV7_735-759 1e-07 0 CL0361 F 733 757 CD  H-Bb H-Mj L-Bb 
zf-H2C2_2 Domain Q9NQV7_763-787 1e-07 0 CL0361 F 761 785 CD  H-Bb H-Mj H-Mn S-Bb L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
E/F=717-858 C chromosome
E/F=717-858 C nucleoplasm
E/F=717-858 C nucleus
E/F=717-858 F histone methyltransferase activity
E/F=717-858 F histone methyltransferase activity (H3-K36 specific)
E/F=717-858 F histone methyltransferase activity (H3-K4 specific)
E/F=717-858 F histone-lysine N-methyltransferase activity
E/F=717-858 F metal ion binding
E/F=717-858 F protein homodimerization activity
E/F=717-858 F recombination hotspot binding
E/F=717-858 F sequence-specific DNA binding
E/F=717-858 F transcription regulatory region sequence-specific DNA binding
E/F=717-858 P double-strand break repair involved in meiotic recombination
E/F=717-858 P female gamete generation
E/F=717-858 P histone H3-K36 dimethylation
E/F=717-858 P histone H3-K36 trimethylation
E/F=717-858 P histone H3-K4 dimethylation
E/F=717-858 P histone H3-K4 methylation
E/F=717-858 P histone H3-K4 monomethylation
E/F=717-858 P histone H3-K4 trimethylation
E/F=717-858 P histone H3-K9 methylation
E/F=717-858 P male gamete generation
E/F=717-858 P meiotic gene conversion
E/F=717-858 P negative regulation of apoptotic process
E/F=717-858 P nucleosome positioning
E/F=717-858 P positive regulation of fertilization
E/F=717-858 P positive regulation of histone H3-K36 trimethylation
E/F=717-858 P positive regulation of histone H3-K4 trimethylation
E/F=717-858 P positive regulation of reciprocal meiotic recombination
E/F=717-858 P regulation of gene expression
E/F=717-858 P regulation of transcription, DNA-templated
E/F=717-858 P synapsis
Sequences
Download file with secondary structure created by Stride  
5eh2.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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F (protein): 
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5eh2.pdb2.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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E (protein): 
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