General information
PDB ID 5HDN
Title CRYSTAL STRUCTURE OF HEAT SHOCK FACTOR1-DBD COMPLEX WITH DS-DNA AND TTT
PDB header TRANSCRIPTION
Date 2016-01-05
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.68
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5hdn.pdb ABCD EFGH 0
Biounits:
5hdn.pdb1.pdb AB EF 1
5hdn.pdb2.pdb CD GH 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HSF_DNA-bind Domain Q00613_18-118 6.7e-36 1 CL0123 A 18 118 EF  H-Bb L-Bb L-Mj 
HSF_DNA-bind Domain Q00613_18-118 8.8e-36 1 CL0123 B 18 118   
HSF_DNA-bind Domain Q00613_18-118 8.3e-36 1 CL0123 C 18 118 G  L-Bb L-Mj 
HSF_DNA-bind Domain Q00613_18-118 2.1e-34 1 CL0123 D 18 118   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C/D=15-120 C centrosome
A/B/C/D=15-120 C chaperone complex
A/B/C/D=15-120 C condensed chromosome kinetochore
A/B/C/D=15-120 C cytoplasm
A/B/C/D=15-120 C cytosol
A/B/C/D=15-120 C euchromatin
A/B/C/D=15-120 C heterochromatin
A/B/C/D=15-120 C host cell nucleus
A/B/C/D=15-120 C kinetochore
A/B/C/D=15-120 C mitotic spindle pole
A/B/C/D=15-120 C nuclear chromatin
A/B/C/D=15-120 C nuclear stress granule
A/B/C/D=15-120 C nucleoplasm
A/B/C/D=15-120 C nucleus
A/B/C/D=15-120 C perinuclear region of cytoplasm
A/B/C/D=15-120 C PML body
A/B/C/D=15-120 C pronucleus
A/B/C/D=15-120 C ribonucleoprotein complex
A/B/C/D=15-120 F chromatin DNA binding
A/B/C/D=15-120 F DNA binding
A/B/C/D=15-120 F DNA-binding transcription factor activity
A/B/C/D=15-120 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B/C/D=15-120 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/B/C/D=15-120 F heat shock protein binding
A/B/C/D=15-120 F Hsp90 protein binding
A/B/C/D=15-120 F identical protein binding
A/B/C/D=15-120 F promoter-specific chromatin binding
A/B/C/D=15-120 F protein heterodimerization activity
A/B/C/D=15-120 F protein kinase binding
A/B/C/D=15-120 F protein self-association
A/B/C/D=15-120 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B/C/D=15-120 F RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
A/B/C/D=15-120 F sequence-specific DNA binding
A/B/C/D=15-120 F sequence-specific double-stranded DNA binding
A/B/C/D=15-120 F sequence-specific single stranded DNA binding
A/B/C/D=15-120 F STAT family protein binding
A/B/C/D=15-120 F translation elongation factor binding
A/B/C/D=15-120 P cellular protein-containing complex assembly
A/B/C/D=15-120 P cellular response to angiotensin
A/B/C/D=15-120 P cellular response to cadmium ion
A/B/C/D=15-120 P cellular response to copper ion
A/B/C/D=15-120 P cellular response to diamide
A/B/C/D=15-120 P cellular response to estradiol stimulus
A/B/C/D=15-120 P cellular response to gamma radiation
A/B/C/D=15-120 P cellular response to heat
A/B/C/D=15-120 P cellular response to hydrogen peroxide
A/B/C/D=15-120 P cellular response to L-glutamine
A/B/C/D=15-120 P cellular response to lipopolysaccharide
A/B/C/D=15-120 P cellular response to nitroglycerin
A/B/C/D=15-120 P cellular response to potassium ion
A/B/C/D=15-120 P cellular response to sodium arsenite
A/B/C/D=15-120 P cellular response to unfolded protein
A/B/C/D=15-120 P defense response
A/B/C/D=15-120 P DNA repair
A/B/C/D=15-120 P embryonic placenta development
A/B/C/D=15-120 P embryonic process involved in female pregnancy
A/B/C/D=15-120 P female meiotic nuclear division
A/B/C/D=15-120 P MAPK cascade
A/B/C/D=15-120 P mRNA processing
A/B/C/D=15-120 P mRNA transcription
A/B/C/D=15-120 P mRNA transport
A/B/C/D=15-120 P negative regulation of cardiac muscle cell apoptotic process
A/B/C/D=15-120 P negative regulation of cell population proliferation
A/B/C/D=15-120 P negative regulation of double-strand break repair via nonhomologous end joining
A/B/C/D=15-120 P negative regulation of inclusion body assembly
A/B/C/D=15-120 P negative regulation of neuron death
A/B/C/D=15-120 P negative regulation of protein-containing complex assembly
A/B/C/D=15-120 P negative regulation of transcription by RNA polymerase II
A/B/C/D=15-120 P negative regulation of tumor necrosis factor production
A/B/C/D=15-120 P positive regulation of apoptotic DNA fragmentation
A/B/C/D=15-120 P positive regulation of cell population proliferation
A/B/C/D=15-120 P positive regulation of cold-induced thermogenesis
A/B/C/D=15-120 P positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
A/B/C/D=15-120 P positive regulation of inclusion body assembly
A/B/C/D=15-120 P positive regulation of microtubule binding
A/B/C/D=15-120 P positive regulation of mitotic cell cycle
A/B/C/D=15-120 P positive regulation of mRNA polyadenylation
A/B/C/D=15-120 P positive regulation of multicellular organism growth
A/B/C/D=15-120 P positive regulation of transcription by RNA polymerase II
A/B/C/D=15-120 P positive regulation of transcription from RNA polymerase II promoter in response to heat stress
A/B/C/D=15-120 P positive regulation of tyrosine phosphorylation of STAT protein
A/B/C/D=15-120 P regulation of cellular response to heat
A/B/C/D=15-120 P regulation of transcription from RNA polymerase II promoter in response to stress
A/B/C/D=15-120 P response to activity
A/B/C/D=15-120 P response to hypobaric hypoxia
A/B/C/D=15-120 P response to nutrient
A/B/C/D=15-120 P response to psychosocial stress
A/B/C/D=15-120 P response to testosterone
A/B/C/D=15-120 P spermatogenesis
A/B/C/D=15-120 P viral process
Sequences
Download file with secondary structure created by Stride  
5hdn.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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B (protein): 
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5hdn.pdb2.pdb:   [ download sequences in FASTA format ]
G (dna): 
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H (dna): 
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C (protein): 
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D (protein): 
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