General information
PDB ID 5IVW
Title HUMAN CORE TFIIH BOUND TO DNA WITHIN THE PIC
PDB header TRANSCRIPTION/DNA
Date 2016-03-21
Experimental method ELECTRON MICROSCOPY
Resolution (A) 10
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5ivw.pdb VW0123 XY 0
Biounits:
5ivw.pdb1.pdb VW0123 XY 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Tfb2_C Domain Q92759_389-456 1.4e-23 1 No_clan 2 389 456   
Tfb4 Domain Q13889_8-231 1.1e-61 1 CL0128 3 8 231   
ERCC3_RAD25_C Domain P19447_496-718 2e-123 1 CL0023 V 496 718 X  H-Bb 
Helicase_C_2 Domain P18074_524-700 3.2e-45 1 CL0023 W 524 700   
HBB Domain P18074_269-413 5.1e-21 1 No_clan W 269 395   
Ssl1 Family Q13888_64-241 3.3e-88 1 CL0128 0 64 241   
Tfb5 Family Q6ZYL4_1-62 1.9e-25 1 No_clan 1 1 62   
Tfb2 Family Q92759_28-274 1e-38 1 No_clan 2 139 405   
Tfb2 Family Q92759_2-60 1.4e-10 1 No_clan 2 28 99   
ResIII Family P19447_313-472 1.6e-15 1 CL0023 V 313 472 XY  L-Bb L-Mn 
DEAD_2 Family P18074_72-256 1.6e-46 1 CL0023 W 72 256   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
0=1-395 C core TFIIH complex portion of holo TFIIH complex
0=1-395 C nuclear speck
0=1-395 C nucleoplasm
0=1-395 C nucleus
0=1-395 C transcription factor TFIID complex
0=1-395 C transcription factor TFIIH core complex
0=1-395 C transcription factor TFIIH holo complex
0=1-395 F protein N-terminus binding
0=1-395 F RNA polymerase II general transcription initiation factor activity
0=1-395 F zinc ion binding
0=1-395 P 7-methylguanosine mRNA capping
0=1-395 P G protein-coupled receptor internalization
0=1-395 P global genome nucleotide-excision repair
0=1-395 P nucleotide-excision repair
0=1-395 P nucleotide-excision repair, DNA duplex unwinding
0=1-395 P nucleotide-excision repair, DNA incision
0=1-395 P nucleotide-excision repair, DNA incision, 3'-to lesion
0=1-395 P nucleotide-excision repair, DNA incision, 5'-to lesion
0=1-395 P nucleotide-excision repair, preincision complex assembly
0=1-395 P nucleotide-excision repair, preincision complex stabilization
0=1-395 P positive regulation of DNA helicase activity
0=1-395 P regulation of transcription by RNA polymerase II
0=1-395 P response to UV
0=1-395 P termination of RNA polymerase I transcription
0=1-395 P transcription by RNA polymerase II
0=1-395 P transcription elongation from RNA polymerase I promoter
0=1-395 P transcription elongation from RNA polymerase II promoter
0=1-395 P transcription initiation from RNA polymerase I promoter
0=1-395 P transcription initiation from RNA polymerase II promoter
0=1-395 P transcription-coupled nucleotide-excision repair
0=1-395 P viral process
1=1-71 C nucleolus
1=1-71 C nucleoplasm
1=1-71 C transcription factor TFIID complex
1=1-71 C transcription factor TFIIH core complex
1=1-71 C transcription factor TFIIH holo complex
1=1-71 P 7-methylguanosine mRNA capping
1=1-71 P cellular response to gamma radiation
1=1-71 P global genome nucleotide-excision repair
1=1-71 P maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
1=1-71 P nucleotide-excision repair
1=1-71 P nucleotide-excision repair, DNA duplex unwinding
1=1-71 P nucleotide-excision repair, DNA incision
1=1-71 P nucleotide-excision repair, DNA incision, 3'-to lesion
1=1-71 P nucleotide-excision repair, DNA incision, 5'-to lesion
1=1-71 P nucleotide-excision repair, preincision complex assembly
1=1-71 P nucleotide-excision repair, preincision complex stabilization
1=1-71 P phosphorylation of RNA polymerase II C-terminal domain
1=1-71 P termination of RNA polymerase I transcription
1=1-71 P transcription by RNA polymerase II
1=1-71 P transcription elongation from RNA polymerase I promoter
1=1-71 P transcription elongation from RNA polymerase II promoter
1=1-71 P transcription initiation from RNA polymerase I promoter
1=1-71 P transcription initiation from RNA polymerase II promoter
1=1-71 P transcription-coupled nucleotide-excision repair
2=1-462 C core TFIIH complex portion of holo TFIIH complex
2=1-462 C nuclear speck
2=1-462 C nucleoplasm
2=1-462 C nucleus
2=1-462 C transcription factor TFIID complex
2=1-462 C transcription factor TFIIH core complex
2=1-462 C transcription factor TFIIH holo complex
2=1-462 F ATPase activator activity
2=1-462 F double-stranded DNA binding
2=1-462 F RNA polymerase II general transcription initiation factor activity
2=1-462 P 7-methylguanosine mRNA capping
2=1-462 P DNA repair
2=1-462 P global genome nucleotide-excision repair
2=1-462 P nucleotide-excision repair
2=1-462 P nucleotide-excision repair, DNA duplex unwinding
2=1-462 P nucleotide-excision repair, DNA incision
2=1-462 P nucleotide-excision repair, DNA incision, 3'-to lesion
2=1-462 P nucleotide-excision repair, DNA incision, 5'-to lesion
2=1-462 P nucleotide-excision repair, preincision complex assembly
2=1-462 P nucleotide-excision repair, preincision complex stabilization
2=1-462 P phosphorylation of RNA polymerase II C-terminal domain
2=1-462 P termination of RNA polymerase I transcription
2=1-462 P transcription by RNA polymerase II
2=1-462 P transcription elongation from RNA polymerase I promoter
2=1-462 P transcription elongation from RNA polymerase II promoter
2=1-462 P transcription initiation from RNA polymerase I promoter
2=1-462 P transcription initiation from RNA polymerase II promoter
2=1-462 P transcription-coupled nucleotide-excision repair
3=1-308 C core TFIIH complex portion of holo TFIIH complex
3=1-308 C nucleoplasm
3=1-308 C nucleus
3=1-308 C transcription factor TFIID complex
3=1-308 C transcription factor TFIIH core complex
3=1-308 C transcription factor TFIIH holo complex
3=1-308 C transcription preinitiation complex
3=1-308 F metal ion binding
3=1-308 F protein N-terminus binding
3=1-308 F RNA polymerase II general transcription initiation factor activity
3=1-308 P 7-methylguanosine mRNA capping
3=1-308 P DNA repair
3=1-308 P global genome nucleotide-excision repair
3=1-308 P nucleotide-excision repair
3=1-308 P nucleotide-excision repair, DNA duplex unwinding
3=1-308 P nucleotide-excision repair, DNA incision
3=1-308 P nucleotide-excision repair, DNA incision, 3'-to lesion
3=1-308 P nucleotide-excision repair, DNA incision, 5'-to lesion
3=1-308 P nucleotide-excision repair, preincision complex assembly
3=1-308 P nucleotide-excision repair, preincision complex stabilization
3=1-308 P phosphorylation of RNA polymerase II C-terminal domain
3=1-308 P termination of RNA polymerase I transcription
3=1-308 P transcription by RNA polymerase II
3=1-308 P transcription elongation from RNA polymerase I promoter
3=1-308 P transcription elongation from RNA polymerase II promoter
3=1-308 P transcription initiation from RNA polymerase I promoter
3=1-308 P transcription initiation from RNA polymerase II promoter
3=1-308 P transcription-coupled nucleotide-excision repair
V=1-782 C nucleoplasm
V=1-782 C nucleotide-excision repair factor 3 complex
V=1-782 C nucleus
V=1-782 C transcription factor TFIID complex
V=1-782 C transcription factor TFIIH core complex
V=1-782 C transcription factor TFIIH holo complex
V=1-782 C transcription preinitiation complex
V=1-782 F 3'-5' DNA helicase activity
V=1-782 F ATP binding
V=1-782 F ATPase activity
V=1-782 F damaged DNA binding
V=1-782 F DNA binding
V=1-782 F DNA helicase activity
V=1-782 F helicase activity
V=1-782 F promoter-specific chromatin binding
V=1-782 F protein C-terminus binding
V=1-782 F protein N-terminus binding
V=1-782 F transcription factor binding
V=1-782 P 7-methylguanosine mRNA capping
V=1-782 P apoptotic process
V=1-782 P DNA repair
V=1-782 P DNA topological change
V=1-782 P embryonic organ development
V=1-782 P global genome nucleotide-excision repair
V=1-782 P hair cell differentiation
V=1-782 P nucleotide-excision repair
V=1-782 P nucleotide-excision repair, DNA duplex unwinding
V=1-782 P nucleotide-excision repair, DNA incision
V=1-782 P nucleotide-excision repair, DNA incision, 3'-to lesion
V=1-782 P nucleotide-excision repair, DNA incision, 5'-to lesion
V=1-782 P nucleotide-excision repair, preincision complex assembly
V=1-782 P nucleotide-excision repair, preincision complex stabilization
V=1-782 P positive regulation of apoptotic process
V=1-782 P protein localization
V=1-782 P protein phosphorylation
V=1-782 P regulation of mitotic cell cycle phase transition
V=1-782 P response to hypoxia
V=1-782 P response to oxidative stress
V=1-782 P response to UV
V=1-782 P termination of RNA polymerase I transcription
V=1-782 P transcription by RNA polymerase II
V=1-782 P transcription elongation from RNA polymerase I promoter
V=1-782 P transcription elongation from RNA polymerase II promoter
V=1-782 P transcription initiation from RNA polymerase I promoter
V=1-782 P transcription initiation from RNA polymerase II promoter
V=1-782 P transcription-coupled nucleotide-excision repair
V=1-782 P UV protection
V=1-782 P viral process
W=1-760 C CAK-ERCC2 complex
W=1-760 C cytoplasm
W=1-760 C cytosol
W=1-760 C MMXD complex
W=1-760 C nucleoplasm
W=1-760 C nucleus
W=1-760 C spindle
W=1-760 C transcription factor TFIID complex
W=1-760 C transcription factor TFIIH core complex
W=1-760 C transcription factor TFIIH holo complex
W=1-760 F 4 iron, 4 sulfur cluster binding
W=1-760 F 5'-3' DNA helicase activity
W=1-760 F ATP binding
W=1-760 F damaged DNA binding
W=1-760 F DNA helicase activity
W=1-760 F metal ion binding
W=1-760 F protein C-terminus binding
W=1-760 F protein N-terminus binding
W=1-760 F protein-macromolecule adaptor activity
W=1-760 P 7-methylguanosine mRNA capping
W=1-760 P aging
W=1-760 P apoptotic process
W=1-760 P bone mineralization
W=1-760 P cell population proliferation
W=1-760 P central nervous system myelin formation
W=1-760 P chromosome segregation
W=1-760 P embryonic cleavage
W=1-760 P embryonic organ development
W=1-760 P erythrocyte maturation
W=1-760 P extracellular matrix organization
W=1-760 P global genome nucleotide-excision repair
W=1-760 P hair cell differentiation
W=1-760 P hair follicle maturation
W=1-760 P hematopoietic stem cell differentiation
W=1-760 P in utero embryonic development
W=1-760 P maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W=1-760 P multicellular organism growth
W=1-760 P nucleotide-excision repair
W=1-760 P nucleotide-excision repair, DNA duplex unwinding
W=1-760 P nucleotide-excision repair, DNA incision
W=1-760 P nucleotide-excision repair, DNA incision, 3'-to lesion
W=1-760 P nucleotide-excision repair, DNA incision, 5'-to lesion
W=1-760 P nucleotide-excision repair, preincision complex assembly
W=1-760 P nucleotide-excision repair, preincision complex stabilization
W=1-760 P positive regulation of DNA binding
W=1-760 P positive regulation of mitotic recombination
W=1-760 P positive regulation of transcription, DNA-templated
W=1-760 P post-embryonic development
W=1-760 P protein phosphorylation
W=1-760 P regulation of mitotic cell cycle phase transition
W=1-760 P regulation of mitotic recombination
W=1-760 P response to hypoxia
W=1-760 P response to oxidative stress
W=1-760 P response to UV
W=1-760 P spinal cord development
W=1-760 P termination of RNA polymerase I transcription
W=1-760 P transcription by RNA polymerase II
W=1-760 P transcription elongation from RNA polymerase I promoter
W=1-760 P transcription elongation from RNA polymerase II promoter
W=1-760 P transcription initiation from RNA polymerase I promoter
W=1-760 P transcription initiation from RNA polymerase II promoter
W=1-760 P transcription-coupled nucleotide-excision repair
W=1-760 P UV protection
W=1-760 P viral process
Sequences
Download file with secondary structure created by Stride  
5ivw.pdb1.pdb:   [ download sequences in FASTA format ]
X (dna): 
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Y (dna): 
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0 (protein): 
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1 (protein): 
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2 (protein): 
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3 (protein): 
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V (protein): 
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W (protein): 
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