General information
PDB ID 5KL4
Title WILMS TUMOR PROTEIN (WT1) ZNF2-4 Q369H IN COMPLEX WITH FORMYLATED DNA
PDB header TRANSCRIPTION/DNA
Date 2016-06-23
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.78
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5kl4.pdb AD BCEF 0
Biounits:
5kl4.pdb1.pdb A BC 1
5kl4.pdb2.pdb D EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-H2C2_2 Domain P19544_371-396 1.6e-07 0 CL0361 A 369 394 BC  H-Bb H-Mj S-Bb L-Bb L-Mj 
zf-H2C2_2 Domain P19544_399-426 2.4e-06 0 CL0361 A 397 424 BC  H-Bb L-Bb L-Mj 
FOXP-CC Domain P19544_409-438 0.00087 0 No_clan A 408 437 BC  H-Bb H-Mj L-Bb L-Mj 
zf-H2C2_2 Domain P19544_371-396 1.5e-07 0 CL0361 D 369 394 EF  H-Bb H-Mj S-Bb L-Bb L-Mj 
zf-H2C2_2 Domain P19544_399-426 2.2e-06 0 CL0361 D 397 424 EF  H-Bb S-Bb L-Bb L-Mj 
FOXP-CC Domain P19544_409-438 0.0009 0 No_clan D 409 436 EF  H-Bb H-Mj S-Bb L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/D=350-440 C cytoplasm
A/D=350-440 C cytosol
A/D=350-440 C nuclear speck
A/D=350-440 C nucleolus
A/D=350-440 C nucleoplasm
A/D=350-440 C nucleus
A/D=350-440 F C2H2 zinc finger domain binding
A/D=350-440 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/D=350-440 F DNA-binding transcription factor activity
A/D=350-440 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/D=350-440 F double-stranded methylated DNA binding
A/D=350-440 F hemi-methylated DNA-binding
A/D=350-440 F RNA binding
A/D=350-440 F sequence-specific DNA binding
A/D=350-440 F transcription regulatory region sequence-specific DNA binding
A/D=350-440 F zinc ion binding
A/D=350-440 P adrenal cortex formation
A/D=350-440 P adrenal gland development
A/D=350-440 P branching involved in ureteric bud morphogenesis
A/D=350-440 P camera-type eye development
A/D=350-440 P cardiac muscle cell fate commitment
A/D=350-440 P cellular response to cAMP
A/D=350-440 P cellular response to gonadotropin stimulus
A/D=350-440 P diaphragm development
A/D=350-440 P epithelial cell differentiation
A/D=350-440 P germ cell development
A/D=350-440 P glomerular basement membrane development
A/D=350-440 P glomerular visceral epithelial cell differentiation
A/D=350-440 P glomerulus development
A/D=350-440 P gonad development
A/D=350-440 P heart development
A/D=350-440 P kidney development
A/D=350-440 P male genitalia development
A/D=350-440 P male gonad development
A/D=350-440 P mesenchymal to epithelial transition
A/D=350-440 P metanephric epithelium development
A/D=350-440 P metanephric mesenchyme development
A/D=350-440 P metanephric S-shaped body morphogenesis
A/D=350-440 P negative regulation of apoptotic process
A/D=350-440 P negative regulation of cell growth
A/D=350-440 P negative regulation of cell population proliferation
A/D=350-440 P negative regulation of female gonad development
A/D=350-440 P negative regulation of metanephric glomerular mesangial cell proliferation
A/D=350-440 P negative regulation of transcription by RNA polymerase II
A/D=350-440 P negative regulation of transcription, DNA-templated
A/D=350-440 P negative regulation of translation
A/D=350-440 P positive regulation of apoptotic process
A/D=350-440 P positive regulation of DNA methylation
A/D=350-440 P positive regulation of gene expression
A/D=350-440 P positive regulation of heart growth
A/D=350-440 P positive regulation of male gonad development
A/D=350-440 P positive regulation of metanephric ureteric bud development
A/D=350-440 P positive regulation of pri-miRNA transcription by RNA polymerase II
A/D=350-440 P positive regulation of transcription by RNA polymerase II
A/D=350-440 P positive regulation of transcription, DNA-templated
A/D=350-440 P posterior mesonephric tubule development
A/D=350-440 P regulation of animal organ formation
A/D=350-440 P regulation of transcription by RNA polymerase II
A/D=350-440 P regulation of transcription, DNA-templated
A/D=350-440 P RNA splicing
A/D=350-440 P sex determination
A/D=350-440 P thorax and anterior abdomen determination
A/D=350-440 P tissue development
A/D=350-440 P ureteric bud development
A/D=350-440 P vasculogenesis
A/D=350-440 P visceral serous pericardium development
Sequences
Download file with secondary structure created by Stride  
5kl4.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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5kl4.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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D (protein): 
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