General information
PDB ID 5LTY
Title HOMEOBOX TRANSCRIPTION FACTOR CDX2 BOUND TO METHYLATED DNA
PDB header TRANSCRIPTION
Date 2016-09-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.66
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5lty.pdb KM ABFE 0
Biounits:
5lty.pdb1.pdb K AF 1
5lty.pdb2.pdb M BE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeodomain Domain Q99626_187-243 4.4e-22 1 CL0123 K 187 243 AF  H-Bb H-Mj L-Bb L-Mn 
Homeodomain Domain Q99626_187-243 4.2e-22 1 CL0123 M 187 243 BE  H-Bb H-Mj L-Bb L-Mn 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
K/M=185-255 C condensed nuclear chromosome
K/M=185-255 C nuclear chromatin
K/M=185-255 C nucleoplasm
K/M=185-255 C nucleus
K/M=185-255 C transcription repressor complex
K/M=185-255 F DNA-binding transcription factor activity
K/M=185-255 F DNA-binding transcription factor activity, RNA polymerase II-specific
K/M=185-255 F DNA-binding transcription repressor activity, RNA polymerase II-specific
K/M=185-255 F methyl-CpG binding
K/M=185-255 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
K/M=185-255 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
K/M=185-255 F sequence-specific double-stranded DNA binding
K/M=185-255 F transcription corepressor activity
K/M=185-255 P animal organ morphogenesis
K/M=185-255 P anterior/posterior axis specification
K/M=185-255 P blood vessel development
K/M=185-255 P cell differentiation
K/M=185-255 P endosome to lysosome transport
K/M=185-255 P establishment or maintenance of epithelial cell apical/basal polarity
K/M=185-255 P intestinal epithelial cell differentiation
K/M=185-255 P labyrinthine layer development
K/M=185-255 P negative regulation of transcription by RNA polymerase II
K/M=185-255 P positive regulation of cell differentiation
K/M=185-255 P positive regulation of cell population proliferation
K/M=185-255 P positive regulation of transcription, DNA-templated
K/M=185-255 P regulation of somitogenesis
K/M=185-255 P regulation of transcription by RNA polymerase II
K/M=185-255 P somatic stem cell population maintenance
K/M=185-255 P trophectodermal cell differentiation
Sequences
Download file with secondary structure created by Stride  
5lty.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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F (dna): 
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K (protein): 
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5lty.pdb2.pdb:   [ download sequences in FASTA format ]
B (dna): 
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E (dna): 
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M (protein): 
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