General information
PDB ID 5ODG
Title CRYSTAL STRUCTURE OF SMAD3-MH1 BOUND TO THE GGCT SITE.
PDB header TRANSCRIPTION
Date 2017-07-05
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.12
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5odg.pdb AB DE 0
Biounits:
5odg.pdb1.pdb AB DE 2
5odg.pdb2.pdb BA DE 2
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MH1 Domain P84022_31-131 8e-45 1 CL0263 A 31 131 DE  S-Bb S-Mj L-Bb L-Mj 
MH1 Domain P84022_31-131 7.8e-45 1 CL0263 B 31 131 DE   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=11-135 C cytoplasm
A/B=11-135 C cytosol
A/B=11-135 C heteromeric SMAD protein complex
A/B=11-135 C nuclear chromatin
A/B=11-135 C nuclear inner membrane
A/B=11-135 C nucleoplasm
A/B=11-135 C nucleus
A/B=11-135 C plasma membrane
A/B=11-135 C receptor complex
A/B=11-135 C SMAD protein complex
A/B=11-135 C transcription regulator complex
A/B=11-135 F beta-catenin binding
A/B=11-135 F bHLH transcription factor binding
A/B=11-135 F chromatin DNA binding
A/B=11-135 F cis-regulatory region sequence-specific DNA binding
A/B=11-135 F co-SMAD binding
A/B=11-135 F collagen binding
A/B=11-135 F DEAD/H-box RNA helicase binding
A/B=11-135 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=11-135 F DNA-binding transcription factor activity
A/B=11-135 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=11-135 F glucocorticoid receptor binding
A/B=11-135 F identical protein binding
A/B=11-135 F mineralocorticoid receptor binding
A/B=11-135 F phosphatase binding
A/B=11-135 F protein homodimerization activity
A/B=11-135 F protein kinase binding
A/B=11-135 F R-SMAD binding
A/B=11-135 F RNA polymerase II activating transcription factor binding
A/B=11-135 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=11-135 F sequence-specific DNA binding
A/B=11-135 F transcription coactivator binding
A/B=11-135 F transcription factor binding
A/B=11-135 F transcription regulatory region sequence-specific DNA binding
A/B=11-135 F transforming growth factor beta receptor binding
A/B=11-135 F ubiquitin binding
A/B=11-135 F ubiquitin protein ligase binding
A/B=11-135 F zinc ion binding
A/B=11-135 P activation of cysteine-type endopeptidase activity involved in apoptotic process
A/B=11-135 P activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
A/B=11-135 P activin receptor signaling pathway
A/B=11-135 P adrenal gland development
A/B=11-135 P cell cycle arrest
A/B=11-135 P cell-cell junction organization
A/B=11-135 P cellular response to cytokine stimulus
A/B=11-135 P cellular response to transforming growth factor beta stimulus
A/B=11-135 P developmental growth
A/B=11-135 P embryonic cranial skeleton morphogenesis
A/B=11-135 P embryonic foregut morphogenesis
A/B=11-135 P embryonic pattern specification
A/B=11-135 P endoderm development
A/B=11-135 P extrinsic apoptotic signaling pathway
A/B=11-135 P heart looping
A/B=11-135 P immune response
A/B=11-135 P immune system development
A/B=11-135 P in utero embryonic development
A/B=11-135 P lens fiber cell differentiation
A/B=11-135 P liver development
A/B=11-135 P mesoderm formation
A/B=11-135 P negative regulation of apoptotic process
A/B=11-135 P negative regulation of cardiac muscle hypertrophy in response to stress
A/B=11-135 P negative regulation of cell growth
A/B=11-135 P negative regulation of cytosolic calcium ion concentration
A/B=11-135 P negative regulation of fat cell differentiation
A/B=11-135 P negative regulation of inflammatory response
A/B=11-135 P negative regulation of lung blood pressure
A/B=11-135 P negative regulation of mitotic cell cycle
A/B=11-135 P negative regulation of osteoblast differentiation
A/B=11-135 P negative regulation of osteoblast proliferation
A/B=11-135 P negative regulation of protein catabolic process
A/B=11-135 P negative regulation of transcription by RNA polymerase II
A/B=11-135 P negative regulation of transforming growth factor beta receptor signaling pathway
A/B=11-135 P negative regulation of wound healing
A/B=11-135 P nodal signaling pathway
A/B=11-135 P osteoblast development
A/B=11-135 P paraxial mesoderm morphogenesis
A/B=11-135 P pericardium development
A/B=11-135 P positive regulation of alkaline phosphatase activity
A/B=11-135 P positive regulation of bone mineralization
A/B=11-135 P positive regulation of canonical Wnt signaling pathway
A/B=11-135 P positive regulation of cell migration
A/B=11-135 P positive regulation of chondrocyte differentiation
A/B=11-135 P positive regulation of DNA-binding transcription factor activity
A/B=11-135 P positive regulation of epithelial to mesenchymal transition
A/B=11-135 P positive regulation of extracellular matrix assembly
A/B=11-135 P positive regulation of focal adhesion assembly
A/B=11-135 P positive regulation of gene expression
A/B=11-135 P positive regulation of interleukin-1 beta production
A/B=11-135 P positive regulation of nitric oxide biosynthetic process
A/B=11-135 P positive regulation of positive chemotaxis
A/B=11-135 P positive regulation of pri-miRNA transcription by RNA polymerase II
A/B=11-135 P positive regulation of protein import into nucleus
A/B=11-135 P positive regulation of stress fiber assembly
A/B=11-135 P positive regulation of transcription by RNA polymerase II
A/B=11-135 P positive regulation of transcription, DNA-templated
A/B=11-135 P positive regulation of transforming growth factor beta3 production
A/B=11-135 P primary miRNA processing
A/B=11-135 P protein deubiquitination
A/B=11-135 P protein stabilization
A/B=11-135 P regulation of binding
A/B=11-135 P regulation of epithelial cell proliferation
A/B=11-135 P regulation of immune response
A/B=11-135 P regulation of striated muscle tissue development
A/B=11-135 P regulation of transcription by RNA polymerase II
A/B=11-135 P regulation of transforming growth factor beta receptor signaling pathway
A/B=11-135 P regulation of transforming growth factor beta2 production
A/B=11-135 P response to hypoxia
A/B=11-135 P signal transduction involved in regulation of gene expression
A/B=11-135 P SMAD protein complex assembly
A/B=11-135 P SMAD protein signal transduction
A/B=11-135 P somitogenesis
A/B=11-135 P T cell activation
A/B=11-135 P thyroid gland development
A/B=11-135 P transdifferentiation
A/B=11-135 P transforming growth factor beta receptor signaling pathway
A/B=11-135 P ureteric bud development
A/B=11-135 P viral process
A/B=11-135 P wound healing
Sequences
Download file with secondary structure created by Stride  
5odg.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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E (dna): 
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A (protein): 
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5odg.pdb2.pdb:   [ download sequences in FASTA format ]
B (protein): 
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